Manganese toxicity in a child with iron deficiency and polycythemia

Résultat de recherche: Articleexamen par les pairs

47 Citations (Scopus)

Résumé

A previously healthy 5-year-old girl presented with pica, emotional lability, and marked gait abnormalities. She had concurrent severe iron deficiency and polycythemia. Her magnetic resonance imaging (MRI) scan showed increased signal in the basal ganglia on T1-weighted images consistent with manganese neurotoxicity. Manganism was subsequently confirmed as her blood manganese levels were extremely elevated. Chelation therapy resulted in improvement in her mobility but she continues to have significant gait impairment. An epidemiological investigation identified well water as the potential source of manganese exposure for our patient, but to date, we have been unable to identify the nature of her neurotoxic susceptibility.

Langue d'origineEnglish
Pages (de-à)891-894
Nombre de pages4
JournalJournal of Child Neurology
Volume26
Numéro de publication7
DOI
Statut de publicationPublished - juill. 2011

ASJC Scopus Subject Areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

PubMed: MeSH publication types

  • Case Reports
  • Journal Article

Empreinte numérique

Plonger dans les sujets de recherche 'Manganese toxicity in a child with iron deficiency and polycythemia'. Ensemble, ils forment une empreinte numérique unique.

Citer