Résumé
Cell surface macromolecules play a crucial role in the biology and pathobiology of flaviviruses, both as receptors for virus entry and as signaling molecules for cell-cell interactions in the processes of vascular permeability and inflammation. This review examines the cell tropism and pathogenesis of flaviviruses from the standpoint of cell surface molecules, which have been implicated as receptors in both virus-cell as well as cell-cell interactions. The emerging picture is one that encompasses extensive regulation and interplay among the invading virus, viral immune complexes, Fc receptors, major histocompatibility complex antigens, and adhesion molecules.
| Langue d'origine | English |
|---|---|
| Titre de la publication principale | Advances in Virus Research |
| Maison d'édition | Academic Press Inc. |
| Pages | 229-274 |
| Nombre de pages | 46 |
| ISBN (imprimé) | 0120398591, 9780120398591 |
| DOI | |
| Statut de publication | Published - 2003 |
Séries de publication
| Prénom | Advances in Virus Research |
|---|---|
| Volume | 59 |
| ISSN (imprimé) | 0065-3527 |
| ISSN (électronique) | 1557-8399 |
Note bibliographique
Funding Information:Research in the author's laboratory was supported by the Canadian Institutes of Health Research and the Natural Sciences and Engineering Research Council of Canada. The author is grateful for the collaboration and advice of many past and present colleagues, including Y. Huang, C. King, A. Issekutz, J. Marshall, C. Osiowy, R. He, S. Wang, B. Innis, A. King, D. Vaughn, K. S. Myint, T. Endy, and M. Mammen.
ASJC Scopus Subject Areas
- Virology
- Infectious Diseases
PubMed: MeSH publication types
- Journal Article
- Research Support, Non-U.S. Gov't
- Review
ODD de l’ONU
Cette action contribue à la réalisation des objectifs de développement durable suivants
