TY - JOUR
T1 - Perspectives on holoprosencephaly
T2 - Part III. Spectra, distinctions, continuities, and discontinuities
AU - Cohen, M. M.
PY - 1989
Y1 - 1989
N2 - This attemps to balance our knowledge of holoprosencephalic spectra and continuities with important distinctions and discontinuities. Prevalence studies and syndrome delineation are briefly reviewed. The following topics receive detailed coverage: human teratogens, special aspects of forebrain and hindbrain malformations, aprosencephaly/atelencephaly, association with neural tube defects, current assessment of 'facial principles', and endocrine abnormalities.
AB - This attemps to balance our knowledge of holoprosencephalic spectra and continuities with important distinctions and discontinuities. Prevalence studies and syndrome delineation are briefly reviewed. The following topics receive detailed coverage: human teratogens, special aspects of forebrain and hindbrain malformations, aprosencephaly/atelencephaly, association with neural tube defects, current assessment of 'facial principles', and endocrine abnormalities.
UR - http://www.scopus.com/inward/record.url?scp=0024427123&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024427123&partnerID=8YFLogxK
U2 - 10.1002/ajmg.1320340232
DO - 10.1002/ajmg.1320340232
M3 - Review article
C2 - 2683788
AN - SCOPUS:0024427123
SN - 0148-7299
VL - 34
SP - 271
EP - 288
JO - American Journal of Medical Genetics
JF - American Journal of Medical Genetics
IS - 2
ER -