TY - JOUR
T1 - Pharmacotherapy of behavioral and psychological symptoms of dementia
T2 - Time for a different paradigm?
AU - Rojas-Fernandez, C. H.
AU - Lanctôt, K. L.
AU - Allen, D. D.
AU - MacKnight, C.
PY - 2001/1/1
Y1 - 2001/1/1
N2 - Behavioral and psychological symptoms of dementia can occur in 60-80% of patients with Alzheimer's disease or other dementing illnesses, and are important in that they are a source of significant caregiver stress and often precipitate nursing home placement. These symptoms, namely, aggression, delusions, hallucinations, apathy, anxiety, and depression, are clinically managed with a variety of psychotropic drugs such as antipsychotics, antidepressants, antiepileptic drugs, and benzodiazepines. Various advances in the neuropathophysiology and pharmacotherapy must be considered in the optimal design of regimens for patients with these symptoms.
AB - Behavioral and psychological symptoms of dementia can occur in 60-80% of patients with Alzheimer's disease or other dementing illnesses, and are important in that they are a source of significant caregiver stress and often precipitate nursing home placement. These symptoms, namely, aggression, delusions, hallucinations, apathy, anxiety, and depression, are clinically managed with a variety of psychotropic drugs such as antipsychotics, antidepressants, antiepileptic drugs, and benzodiazepines. Various advances in the neuropathophysiology and pharmacotherapy must be considered in the optimal design of regimens for patients with these symptoms.
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U2 - 10.1592/phco.21.1.74.34437
DO - 10.1592/phco.21.1.74.34437
M3 - Review article
C2 - 11191740
AN - SCOPUS:0035174953
SN - 0277-0008
VL - 21
SP - 74
EP - 102
JO - Pharmacotherapy
JF - Pharmacotherapy
IS - 1
ER -