Résumé
Awareness of the human health benefits of blueberries is underpinned by a growing body of positive scientific evidence from human observational and clinical research, plus mechanistic research using animal and in vitro models. Blueberries contain a large number of phytochemicals, including abundant anthocyanin pigments. Of their various phytochemicals, anthocyanins probably make the greatest impact on blueberry health functionality. Epidemiological studies associate regular, moderate intake of blueberries and/or anthocyanins with reduced risk of cardiovascular disease, death, and type 2 diabetes, and with improved weight maintenance and neuroprotection. These findings are supported by biomarker-based evidence from human clinical studies. Among the more important healthful aspects of blueberries are their anti-inflammatory and antioxidant actions and their beneficial effects on vascular and glucoregulatory function. Blueberry phytochemicals may affect gastrointestinal microflora and contribute to host health. These aspects have implications in degenerative diseases and conditions as well as the aging process. More evidence, and particularly human clinical evidence, is needed to better understand the potential for anthocyanin-rich blueberries to benefit public health. However, it is widely agreed that the regular consumption of tasty, ripe blueberries can be unconditionally recommended.
Langue d'origine | English |
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Pages (de-à) | 224-236 |
Nombre de pages | 13 |
Journal | Advances in Nutrition |
Volume | 11 |
Numéro de publication | 2 |
DOI | |
Statut de publication | Published - mars 1 2020 |
Note bibliographique
Funding Information:RZ-R thanks the “Miguel Servet” program (CP15/00100) from the Institute of Health Carlos III (Spain) and the European Social Fund. The authors’ responsibilities were as follows—WK: edited the manuscript and also co-authored content on blueberries and vision; WK, AC, LRH, RK, AJS, FT, RZ-R: each prepared a draft on their topic; and all authors: reviewed and could revise subsequent versions received from the editor (WK) and read and approved the final manuscript.
Funding Information:
The United States Highbush Blueberry Council (USHBC) offered support for this article by providing an honorarium to each author but had no role in the design and conduct of the review. Author disclosures: AC, LRH, RZ-R, no conflicts of interest. AC acts as an advisor to the USHBC grant committee and has received research support from the USHBC. RK, WK, AJS, and FT have received research funding from the USHBC and have no conflict of interest.The USHBC is an agricultural federal research and promotion board established by the USDA. It was founded by and is funded by its members who are blueberry farmers, processors, and importers. The USHBC does not sell any product and operates with independent oversight from the USDA. Address correspondence to WK (e-mail: Wilhelmina.kalt@icloud.com). Abbreviations used: BW, body weight; CVD, cardiovascular disease; RGC, retinal ganglion cell; RPE, retinal pigmentary epithelium; T2DM, type 2 diabetes mellitus.
Publisher Copyright:
© American Society for Nutrition 2019.
ASJC Scopus Subject Areas
- Food Science
- Medicine (miscellaneous)
- Nutrition and Dietetics