TY - JOUR
T1 - Searching for an operational definition of frailty
T2 - A delphi method based consensus statement. the frailty operative definition-consensus conference project
AU - Rodríguez-Mañas, Leocadio
AU - Féart, Catherine
AU - Mann, Giovanni
AU - Viña, Jose
AU - Chatterji, Somnath
AU - Chodzko-Zajko, Wojtek
AU - Gonzalez-Colaço Harmand, Magali
AU - Bergman, Howard
AU - Carcaillon, Laure
AU - Nicholson, Caroline
AU - Scuteri, Angelo
AU - Sinclair, Alan
AU - Pelaez, Martha
AU - Van Der Cammen, Tischa
AU - Beland, François
AU - Bickenbach, Jerome
AU - Delamarche, Paul
AU - Ferrucci, Luigi
AU - Fried, Linda P.
AU - Gutiérrez-Robledo, Luis Miguel
AU - Rockwood, Kenneth
AU - Rodríguez Artalejo, Fernando
AU - Serviddio, Gaetano
AU - Vega, Enrique
N1 - Funding Information:
Supported by EU HEALTH 261270 ) program, Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad ( RD06/0013 ), Instituto de Salud Carlos III, Ministry of Science and Innovation , Spain and by the Intramural Research Program of the National Institute on Aging, National Institutes of Health , USA.
PY - 2013/1
Y1 - 2013/1
N2 - Background.There is no consensus regarding the definition of frailty for clinical uses.Methods.A modified Delphi process was used to attempt to achieve consensus definition. Experts were selected from different fields and organized into five Focus Groups. A questionnaire was developed and sent to experts in the area of frailty. Responses and comments were analyzed using a pre-established strategy. Statements with an agreement more than or equal to 80% were accepted.Results.Overall, 44% of the statements regarding the concept of frailty and 18% of the statements regarding diagnostic criteria were accepted. There was consensus on the value of screening for frailty and about the identification of six domains of frailty for inclusion in a clinical definition, but no agreement was reached concerning a specific set of clinical/laboratory biomarkers useful for diagnosis.Conclusions.There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions. However, additional research is needed before an operative definition of frailty can be established.
AB - Background.There is no consensus regarding the definition of frailty for clinical uses.Methods.A modified Delphi process was used to attempt to achieve consensus definition. Experts were selected from different fields and organized into five Focus Groups. A questionnaire was developed and sent to experts in the area of frailty. Responses and comments were analyzed using a pre-established strategy. Statements with an agreement more than or equal to 80% were accepted.Results.Overall, 44% of the statements regarding the concept of frailty and 18% of the statements regarding diagnostic criteria were accepted. There was consensus on the value of screening for frailty and about the identification of six domains of frailty for inclusion in a clinical definition, but no agreement was reached concerning a specific set of clinical/laboratory biomarkers useful for diagnosis.Conclusions.There is agreement on the usefulness of defining frailty in clinical settings as well as on its main dimensions. However, additional research is needed before an operative definition of frailty can be established.
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U2 - 10.1093/gerona/gls119
DO - 10.1093/gerona/gls119
M3 - Article
C2 - 22511289
AN - SCOPUS:84871909591
SN - 1079-5006
VL - 68
SP - 62
EP - 67
JO - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
JF - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
IS - 1
ER -