Sleep Variables as Predictors of Treatment Effectiveness and Side Effects of Stimulant Medication in Newly Diagnosed Children with Attention-Deficit/Hyperactivity Disorder

Fiona Davidson, Gabrielle Rigney, Benjamin Rusak, Christine Chambers, Malgorzata Rajda, Penny Corkum

Résultat de recherche: Articleexamen par les pairs

3 Citations (Scopus)

Résumé

OBJECTIVE: There is a growing body of research on the impact of stimulant medication on sleep in children with attention-deficit/hyperactivity disorder (ADHD). Negative sleep side effects are a common reason for nonadherence or for discontinuing a course of treatment. However, there is no published evidence as to whether pretreatment sleep can predict responses to treatment and the emergence of side effects. METHOD: In this study, baseline sleep variables were used to predict therapeutic effect (i.e., reduction of ADHD symptoms) and side effects (both sleep and global side effects) in a sample of newly diagnosed, medication-naive children (n = 50). RESULTS: The results of hierarchical regression analysis showed that parent-reported shorter sleep duration before medication treatment significantly predicted better response to treatment, independent of pretreatment ADHD symptoms. Baseline sleep features did not significantly predict global (nonsleep) side effects but did predict increased sleep side effects during treatment. CONCLUSION: These results indicate that baseline sleep variables may be helpful in predicting therapeutic response to medication and sleep disturbance as a side effect of stimulant medication.

Langue d'origineEnglish
Pages (de-à)1-8
Nombre de pages8
JournalJournal of Developmental and Behavioral Pediatrics
Volume42
Numéro de publication1
DOI
Statut de publicationPublished - janv. 1 2021

Note bibliographique

Publisher Copyright:
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

ASJC Scopus Subject Areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology
  • Psychiatry and Mental health

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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