SnapShot: Cancer Immunotherapy with Oncolytic Viruses

Shashi Gujar; John Bell; Jean Simon Diallo

doi:10.1016/j.cell.2019.01.051

SnapShot: Cancer Immunotherapy with Oncolytic Viruses

Shashi Gujar, John Bell, Jean Simon Diallo

Medicine

Résultat de recherche: Short survey › examen par les pairs

70 Citations (Scopus)

Résumé

Oncolytic viruses (OVs) preferentially infect and kill cancer cells without harming normal cells. OVs can revert cancer-associated immune suppression and initiate clinically meaningful antitumor immune responses. OVs and their resultant immunological events can act at both primary and metastatic sites. Thus, OVs can be exploited for cancer gene therapies and immunotherapies alone or in combination with other interventions, including immune checkpoint blockade.

Langue d'origine	English
Pages (de-à)	1240-1240.e1
Journal	Cell
Volume	176
Numéro de publication	5
DOI	https://doi.org/10.1016/j.cell.2019.01.051
Statut de publication	Published - févr. 21 2019

Note bibliographique

Publisher Copyright:
© 2019

ASJC Scopus Subject Areas

General Biochemistry,Genetics and Molecular Biology

ODD de l’ONU

Cette action contribue à la réalisation des objectifs de développement durable suivants

Accès au document

10.1016/j.cell.2019.01.051

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abstract = "Oncolytic viruses (OVs) preferentially infect and kill cancer cells without harming normal cells. OVs can revert cancer-associated immune suppression and initiate clinically meaningful antitumor immune responses. OVs and their resultant immunological events can act at both primary and metastatic sites. Thus, OVs can be exploited for cancer gene therapies and immunotherapies alone or in combination with other interventions, including immune checkpoint blockade.",

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T2 - Cancer Immunotherapy with Oncolytic Viruses

AU - Gujar, Shashi

AU - Bell, John

AU - Diallo, Jean Simon

PY - 2019/2/21

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N2 - Oncolytic viruses (OVs) preferentially infect and kill cancer cells without harming normal cells. OVs can revert cancer-associated immune suppression and initiate clinically meaningful antitumor immune responses. OVs and their resultant immunological events can act at both primary and metastatic sites. Thus, OVs can be exploited for cancer gene therapies and immunotherapies alone or in combination with other interventions, including immune checkpoint blockade.

AB - Oncolytic viruses (OVs) preferentially infect and kill cancer cells without harming normal cells. OVs can revert cancer-associated immune suppression and initiate clinically meaningful antitumor immune responses. OVs and their resultant immunological events can act at both primary and metastatic sites. Thus, OVs can be exploited for cancer gene therapies and immunotherapies alone or in combination with other interventions, including immune checkpoint blockade.

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SnapShot: Cancer Immunotherapy with Oncolytic Viruses

Résumé

Note bibliographique

ASJC Scopus Subject Areas

ODD de l’ONU

Accès au document

Autres fichiers et liens

Empreinte numérique

Citer