Résumé
Background: Goal Attainment Scaling (GAS) is an individualized outcome measure that allows the setting of personalized treatment goals. We compared the responsiveness of GAS when individuals set only one goal instead of the recommended three or more goals. Methods: We conducted exploratory analyses on data from two randomized controlled trials: the Video-Imaging Synthesis of Treating Alzheimer’s Disease (VISTA) (n = 130); and the Mobile Geriatric Assessment Team (MGAT) (n = 265). Independent t-tests and standardized response means (SRMs) were used to assess responsiveness of one- vs. multiple-goal GAS. Results: In VISTA, clinician-rated multiple-goal GAS detected higher goal attainment in the intervention group (p = 0.01; SRM = 0.48). One-goal GAS, whether rated by patients or by clinicians, did not detect differences in goal attainment between groups (patient: p = 0.56, SRM = 0.10; clinician: p = 0.10, SRM = 0.29). In MGAT, multiple-goal GAS (outcome goals: p <.001, SRM = 1.29; total goals: p <.001, SRM = 1.52) and one-goal GAS (outcome goals: p <.001, SRM = 0.89; total goals: p <.001, SRM = 0.75), detected significantly higher goal attainment in the intervention group. Conclusion: One-goal GAS detected significant change in response to a patient-centred, multi-domain care initiative. As such, in similar contexts, one-goal GAS may be an effective means of optimizing personalization and improving GAS feasibility through reduced administration time. However, it is not yet clear if one-goal GAS is responsive in the context of a pharmacological intervention and further research is recommended.
| Langue d'origine | English |
|---|---|
| Numéro d'article | 35 |
| Journal | Journal of Patient-Reported Outcomes |
| Volume | 4 |
| Numéro de publication | 1 |
| DOI | |
| Statut de publication | Published - déc. 1 2020 |
Note bibliographique
Funding Information:LM received a postdoctoral fellowship from the Mitacs Elevate program (Ref: IT09427). KR receives career support from the Dalhousie Medical Research Foundation as the Kathryn Allen Weldon Professor of Alzheimer Research, and research support through grants from the Canadian Institutes of Health Research, the Canadian Frailty Network, the Nova Scotia Health Research Foundation, the Nova Scotia Health Authority Research Fund, and the Fountain Family Innovation Fund of the QEII Health Science Centre Foundation. Acknowledgements
Funding Information:
LM received a postdoctoral fellowship from the Mitacs Elevate program and the Mitacs industrial co-sponsor is DGI Clinical, Halifax, Nova Scotia, Canada. In addition to academic and hospital appointments, KR is President and Chief Science Officer of DGI Clinical, which in the last five years has contracts with pharma and device manufacturers (Baxter, Baxalta, Biogen, Shire, Hollister, Nutricia, Roche, Otsuka) on individualized outcome measurement. In 2017 he attended an advisory board meeting with Lundbeck. Otherwise any personal fees are for invited guest lectures, rounds and academic symposia, received directly from event organizers, for presentations on frailty. He is Associate Director of the Canadian Consortium on Neurodegeneration in Aging, which is funded by the Canadian Institutes of Health Research (CNA-137794), with additional funding from the Alzheimer Society of Canada and several other charities, as well as from Pfizer Canada and Sanofi Canada (in Phase 1, 2014-2019).
Publisher Copyright:
© 2020, The Author(s).
ASJC Scopus Subject Areas
- Health Informatics
- Health Information Management