Résumé
A fatality following ingestion of the drug baclofen (Lioresal®) is described. Baclofen was identified in urine by gas chromatography/mass spectrometry. After derivatization with trinitrobenzene sulfonic acid, baclofen was quantitated in serum and urine by high-performance liquid chromatography. The concentration of baclofen was 17 mg/L in serum and 760 mg/L in urine collected approximately 12 h after the overdose. To our knowledge, this is only the second reported fatality involving a baclofen overdose. The previous case did not include quantitation of baclofen in any biological fluid.
| Langue d'origine | English |
|---|---|
| Pages (de-à) | 1596-1602 |
| Nombre de pages | 7 |
| Journal | Journal of Forensic Sciences |
| Volume | 36 |
| Numéro de publication | 5 |
| DOI | |
| Statut de publication | Published - 1991 |
| Publié à l'externe | Oui |
ASJC Scopus Subject Areas
- Pathology and Forensic Medicine
- Genetics
PubMed: MeSH publication types
- Case Reports
- Journal Article