Treatment of benign prostatic hypertrophy with medrogestone

Robert E. Rangno, Peter J. McLeod, John Ruedy, R. I. Ogilvie

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28 Citations (Scopus)

Résumé

Twenty-four patients with established benign prostatic hypertrophy (BPH) were treated at random in a double-blind manner with one of two drug schedules: medrogestone for 24 weeks followed by placebo for 24 weeks, or the reverse order. Analysis of effects of treatment was made by assessment of frequency, nocturia, hesitancy, intermittency, force and size of urine stream, digital grading of prostate size, residual urine measured isotopically, cystoscopy with prostate needle biopsies, and cystogram. Medrogestone produced a significant reduction in the severity of BPH.

Langue d'origineEnglish
Pages (de-à)658-665
Nombre de pages8
JournalClinical Pharmacology and Therapeutics
Volume12
Numéro de publication4
DOI
Statut de publicationPublished - 1971
Publié à l'externeOui

ASJC Scopus Subject Areas

  • Pharmacology
  • Pharmacology (medical)

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