Alterações topográficas do disco óptico provocadas pela ingestão oral de glicerina

Marcelo Teixeira Nicolela; Roberto Murillo L. De Souza Carvalho; Sylvia Pasternak; Adriana Borges Da Silva; Remo Susanna

doi:10.1590/s0004-27492002000400006

Alterações topográficas do disco óptico provocadas pela ingestão oral de glicerina

Translated title of the contribution: Effects of ingestion of glycerol on optic disc topography

Marcelo Teixeira Nicolela, Roberto Murillo L. De Souza Carvalho, Sylvia Pasternak, Adriana Borges Da Silva, Remo Susanna

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: To verify the effects on optic disc topography of newly diagnosed glaucoma subjects after ingestion of glycerol, a drug that causes major changes in both the intra-ocular pressure (IOP) and cerebrospinal fluid pressure (CSFP). Methods: We studied 14 patients presenting with intra-ocular pressure over 25 mmHg, without previous use of hypotensive therapy. Results: Glycerol produced a significant intra-ocular pressure average reduction of 28.2% (95% CI of 20.7 to 32.1%). Despite the obtained intraocular pressure reduction, no significant change was observed in any evaluated topographic parameter (cup area and volume, rim area and volume, maximal and mean cup depth). Conclusions: Overall, no significant change in the topographic parameters, using the "Heildelberg Retina Tomograph", was observed after ingestion of glycerol.

Translated title of the contribution	Effects of ingestion of glycerol on optic disc topography
Original language	Portuguese
Pages (from-to)	427-429
Number of pages	3
Journal	Arquivos Brasileiros de Oftalmologia
Volume	65
Issue number	4
DOIs	https://doi.org/10.1590/s0004-27492002000400006
Publication status	Published - 2002
Externally published	Yes

ASJC Scopus Subject Areas

Ophthalmology

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10.1590/s0004-27492002000400006

Cite this

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title = "Altera{\c c}{\~o}es topogr{\'a}ficas do disco {\'o}ptico provocadas pela ingest{\~a}o oral de glicerina",

abstract = "Purpose: To verify the effects on optic disc topography of newly diagnosed glaucoma subjects after ingestion of glycerol, a drug that causes major changes in both the intra-ocular pressure (IOP) and cerebrospinal fluid pressure (CSFP). Methods: We studied 14 patients presenting with intra-ocular pressure over 25 mmHg, without previous use of hypotensive therapy. Results: Glycerol produced a significant intra-ocular pressure average reduction of 28.2% (95% CI of 20.7 to 32.1%). Despite the obtained intraocular pressure reduction, no significant change was observed in any evaluated topographic parameter (cup area and volume, rim area and volume, maximal and mean cup depth). Conclusions: Overall, no significant change in the topographic parameters, using the {"}Heildelberg Retina Tomograph{"}, was observed after ingestion of glycerol.",

author = "Nicolela, {Marcelo Teixeira} and {De Souza Carvalho}, {Roberto Murillo L.} and Sylvia Pasternak and {Da Silva}, {Adriana Borges} and Remo Susanna",

year = "2002",

doi = "10.1590/s0004-27492002000400006",

language = "Portugais",

volume = "65",

pages = "427--429",

journal = "Arquivos Brasileiros de Oftalmologia",

issn = "0004-2749",

publisher = "Conselho Brasileiro De Oftalmologia",

number = "4",

}

TY - JOUR

T1 - Alterações topográficas do disco óptico provocadas pela ingestão oral de glicerina

AU - Nicolela, Marcelo Teixeira

AU - De Souza Carvalho, Roberto Murillo L.

AU - Pasternak, Sylvia

AU - Da Silva, Adriana Borges

AU - Susanna, Remo

PY - 2002

Y1 - 2002

N2 - Purpose: To verify the effects on optic disc topography of newly diagnosed glaucoma subjects after ingestion of glycerol, a drug that causes major changes in both the intra-ocular pressure (IOP) and cerebrospinal fluid pressure (CSFP). Methods: We studied 14 patients presenting with intra-ocular pressure over 25 mmHg, without previous use of hypotensive therapy. Results: Glycerol produced a significant intra-ocular pressure average reduction of 28.2% (95% CI of 20.7 to 32.1%). Despite the obtained intraocular pressure reduction, no significant change was observed in any evaluated topographic parameter (cup area and volume, rim area and volume, maximal and mean cup depth). Conclusions: Overall, no significant change in the topographic parameters, using the "Heildelberg Retina Tomograph", was observed after ingestion of glycerol.

AB - Purpose: To verify the effects on optic disc topography of newly diagnosed glaucoma subjects after ingestion of glycerol, a drug that causes major changes in both the intra-ocular pressure (IOP) and cerebrospinal fluid pressure (CSFP). Methods: We studied 14 patients presenting with intra-ocular pressure over 25 mmHg, without previous use of hypotensive therapy. Results: Glycerol produced a significant intra-ocular pressure average reduction of 28.2% (95% CI of 20.7 to 32.1%). Despite the obtained intraocular pressure reduction, no significant change was observed in any evaluated topographic parameter (cup area and volume, rim area and volume, maximal and mean cup depth). Conclusions: Overall, no significant change in the topographic parameters, using the "Heildelberg Retina Tomograph", was observed after ingestion of glycerol.

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DO - 10.1590/s0004-27492002000400006

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Alterações topográficas do disco óptico provocadas pela ingestão oral de glicerina

Abstract

ASJC Scopus Subject Areas

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