Abstract
Frailty was introduced to explain why people of the same age have varying degrees of risk. The deficit accumulation approach shows that as people age, they accumulate health deficits, and that more deficits confer greater risk. Frailty results because not everyone of the same age has the same number of deficits. This is readily quantified using a frailty index, which has been translated to preclinical models. The frailty index grades risk without requiring special instrumentation. It allows a central clinical challenge to be addressed, which is that with age, diseases rarely travel alone.
| Original language | English |
|---|---|
| Pages (from-to) | 1046-1050 |
| Number of pages | 5 |
| Journal | Canadian Journal of Cardiology |
| Volume | 32 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sept 1 2016 |
Bibliographical note
Funding Information:The work referred to here from our group was supported by sequential grants from the Canadian Institute of Health Research (to Dr Kenneth Rockwood and to Dr Arnold Mitnitski) and the support of the Dalhousie Medical Research Foundation (including support to Dr Kenneth Rockwood as the Kathryn Allen Weldon Professor of Alzheimer Research) and the Fountain Family Innovation Fund of the Queen Elizabeth II Health Sciences Foundation.
Publisher Copyright:
© 2016
ASJC Scopus Subject Areas
- Cardiology and Cardiovascular Medicine
PubMed: MeSH publication types
- Journal Article
- Research Support, Non-U.S. Gov't
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Rockwood, K. (2016). Conceptual Models of Frailty: Accumulation of Deficits. Canadian Journal of Cardiology, 32(9), 1046-1050. https://doi.org/10.1016/j.cjca.2016.03.020