Conceptual Models of Frailty: Accumulation of Deficits

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Resumen

Frailty was introduced to explain why people of the same age have varying degrees of risk. The deficit accumulation approach shows that as people age, they accumulate health deficits, and that more deficits confer greater risk. Frailty results because not everyone of the same age has the same number of deficits. This is readily quantified using a frailty index, which has been translated to preclinical models. The frailty index grades risk without requiring special instrumentation. It allows a central clinical challenge to be addressed, which is that with age, diseases rarely travel alone.

Idioma originalEnglish
Páginas (desde-hasta)1046-1050
Número de páginas5
PublicaciónCanadian Journal of Cardiology
Volumen32
N.º9
DOI
EstadoPublished - sep. 1 2016

Nota bibliográfica

Funding Information:
The work referred to here from our group was supported by sequential grants from the Canadian Institute of Health Research (to Dr Kenneth Rockwood and to Dr Arnold Mitnitski) and the support of the Dalhousie Medical Research Foundation (including support to Dr Kenneth Rockwood as the Kathryn Allen Weldon Professor of Alzheimer Research) and the Fountain Family Innovation Fund of the Queen Elizabeth II Health Sciences Foundation.

Publisher Copyright:
© 2016

ASJC Scopus Subject Areas

  • Cardiology and Cardiovascular Medicine

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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