Homologous adoptive cutaneous anaphylaxis (HoACA) - a method which detects IgG antibody in the mouse at the cellular level

Leon S. Kind, Elizabeth Allaway

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We describe a new method, homologous adoptive cutaneous anaphylaxis (HoACA). HoACA will detect IgG at the cellular level if mice are immunized in such a manner that no IgE is synthesized. HoACA could be utilized for the same purposes as a previously described method, heterologous adoptive cutaneous anaphylaxis (HACA). HACA detects IgE at the cellular level and has been used primarily to study the establishment of tolerance. It has also been used for localizing the site of IgE formation and for determining the effect of drugs on IgE formation.

Original languageEnglish
Pages (from-to)83-89
Number of pages7
JournalJournal of Immunological Methods
Volume61
Issue number1
DOIs
Publication statusPublished - Jun 24 1983

ASJC Scopus Subject Areas

  • Immunology and Allergy
  • Immunology

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