Homologous adoptive cutaneous anaphylaxis (HoACA) - a method which detects IgG antibody in the mouse at the cellular level

Leon S. Kind, Elizabeth Allaway

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Resumen

We describe a new method, homologous adoptive cutaneous anaphylaxis (HoACA). HoACA will detect IgG at the cellular level if mice are immunized in such a manner that no IgE is synthesized. HoACA could be utilized for the same purposes as a previously described method, heterologous adoptive cutaneous anaphylaxis (HACA). HACA detects IgE at the cellular level and has been used primarily to study the establishment of tolerance. It has also been used for localizing the site of IgE formation and for determining the effect of drugs on IgE formation.

Idioma originalEnglish
Páginas (desde-hasta)83-89
Número de páginas7
PublicaciónJournal of Immunological Methods
Volumen61
N.º1
DOI
EstadoPublished - jun. 24 1983

ASJC Scopus Subject Areas

  • Immunology and Allergy
  • Immunology

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