Increases in depression after cholesterol-lowering drug treatment

Karina W. Davidson; Sethu Reddy; Patrick McGrath; David Zitner; William Mackeen

doi:10.1080/08964289.1996.9933768

Increases in depression after cholesterol-lowering drug treatment

Karina W. Davidson, Sethu Reddy, Patrick McGrath, David Zitner, William Mackeen

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

To investigate the possibility that increases in depressive symptoms might occur in patients who have undergone cholesterol-lowering interventions, the authors administered the Center for Epidemiological Studies-Depression scale before and after cholesterol lowering to 6 men who were referred to a lipid clinic. All of the patients' cholesterol levels were reduced after the 6-week intervention, and 4 of the patients' depression scores increased; scores of 2 of the 4 met the criteria for mild clinical depression. Further study of possible links among low cholesterol, depressive symptoms, and serotonergic activity is needed.

Original language	English
Pages (from-to)	82-84
Number of pages	3
Journal	Behavioral Medicine
Volume	22
Issue number	2
DOIs	https://doi.org/10.1080/08964289.1996.9933768
Publication status	Published - 1996
Externally published	Yes

Bibliographical note

Funding Information:
This research was supported by the Heart and Stroke Foundation of Nova Scotia. We thank Sandra McFadyen and Michael MacGregor for data collection, and Sandra McFadyen and William F. Chaplin for comments on an earlier version of this article.

ASJC Scopus Subject Areas

Applied Psychology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1080/08964289.1996.9933768

Cite this

@article{ea309fe0cd4b4a77ac2f94d91dda6b4d,

title = "Increases in depression after cholesterol-lowering drug treatment",

abstract = "To investigate the possibility that increases in depressive symptoms might occur in patients who have undergone cholesterol-lowering interventions, the authors administered the Center for Epidemiological Studies-Depression scale before and after cholesterol lowering to 6 men who were referred to a lipid clinic. All of the patients' cholesterol levels were reduced after the 6-week intervention, and 4 of the patients' depression scores increased; scores of 2 of the 4 met the criteria for mild clinical depression. Further study of possible links among low cholesterol, depressive symptoms, and serotonergic activity is needed.",

author = "Davidson, {Karina W.} and Sethu Reddy and Patrick McGrath and David Zitner and William Mackeen",

note = "Funding Information: This research was supported by the Heart and Stroke Foundation of Nova Scotia. We thank Sandra McFadyen and Michael MacGregor for data collection, and Sandra McFadyen and William F. Chaplin for comments on an earlier version of this article.",

year = "1996",

doi = "10.1080/08964289.1996.9933768",

language = "English",

volume = "22",

pages = "82--84",

journal = "Behavioral Medicine",

issn = "0896-4289",

publisher = "Routledge",

number = "2",

}

TY - JOUR

T1 - Increases in depression after cholesterol-lowering drug treatment

AU - Davidson, Karina W.

AU - Reddy, Sethu

AU - McGrath, Patrick

AU - Zitner, David

AU - Mackeen, William

N1 - Funding Information: This research was supported by the Heart and Stroke Foundation of Nova Scotia. We thank Sandra McFadyen and Michael MacGregor for data collection, and Sandra McFadyen and William F. Chaplin for comments on an earlier version of this article.

PY - 1996

Y1 - 1996

N2 - To investigate the possibility that increases in depressive symptoms might occur in patients who have undergone cholesterol-lowering interventions, the authors administered the Center for Epidemiological Studies-Depression scale before and after cholesterol lowering to 6 men who were referred to a lipid clinic. All of the patients' cholesterol levels were reduced after the 6-week intervention, and 4 of the patients' depression scores increased; scores of 2 of the 4 met the criteria for mild clinical depression. Further study of possible links among low cholesterol, depressive symptoms, and serotonergic activity is needed.

AB - To investigate the possibility that increases in depressive symptoms might occur in patients who have undergone cholesterol-lowering interventions, the authors administered the Center for Epidemiological Studies-Depression scale before and after cholesterol lowering to 6 men who were referred to a lipid clinic. All of the patients' cholesterol levels were reduced after the 6-week intervention, and 4 of the patients' depression scores increased; scores of 2 of the 4 met the criteria for mild clinical depression. Further study of possible links among low cholesterol, depressive symptoms, and serotonergic activity is needed.

UR - http://www.scopus.com/inward/record.url?scp=0029819651&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029819651&partnerID=8YFLogxK

U2 - 10.1080/08964289.1996.9933768

DO - 10.1080/08964289.1996.9933768

M3 - Article

AN - SCOPUS:0029819651

SN - 0896-4289

VL - 22

SP - 82

EP - 84

JO - Behavioral Medicine

JF - Behavioral Medicine

IS - 2

ER -

Increases in depression after cholesterol-lowering drug treatment

Abstract

Bibliographical note

ASJC Scopus Subject Areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this