Increases in depression after cholesterol-lowering drug treatment

Karina W. Davidson, Sethu Reddy, Patrick McGrath, David Zitner, William Mackeen

Résultat de recherche: Articleexamen par les pairs

10 Citations (Scopus)

Résumé

To investigate the possibility that increases in depressive symptoms might occur in patients who have undergone cholesterol-lowering interventions, the authors administered the Center for Epidemiological Studies-Depression scale before and after cholesterol lowering to 6 men who were referred to a lipid clinic. All of the patients' cholesterol levels were reduced after the 6-week intervention, and 4 of the patients' depression scores increased; scores of 2 of the 4 met the criteria for mild clinical depression. Further study of possible links among low cholesterol, depressive symptoms, and serotonergic activity is needed.

Langue d'origineEnglish
Pages (de-à)82-84
Nombre de pages3
JournalBehavioral Medicine
Volume22
Numéro de publication2
DOI
Statut de publicationPublished - 1996
Publié à l'externeOui

Note bibliographique

Funding Information:
This research was supported by the Heart and Stroke Foundation of Nova Scotia. We thank Sandra McFadyen and Michael MacGregor for data collection, and Sandra McFadyen and William F. Chaplin for comments on an earlier version of this article.

ASJC Scopus Subject Areas

  • Applied Psychology
  • Psychiatry and Mental health

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