Modeling leukemogenesis in the Zebrafish using genetic and xenograftmodels

Vinothkumar Rajan; Graham Dellaire; Jason N. Berman

doi:10.1007/978-1-4939-3771-4_12

Modeling leukemogenesis in the Zebrafish using genetic and xenograftmodels

Vinothkumar Rajan, Graham Dellaire, Jason N. Berman

Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Citations (Scopus)

Abstract

The zebrafish is a widely accepted model to study leukemia. The major advantage of studying leukemogenesis in zebrafish is attributed to its short life cycle and superior imaging capacity. This chapter highlights using transgenic-and xenograft-based models in zebrafish to study a specific leukemogenic mutation and analyze therapeutic responses in vivo.

Original language	English
Title of host publication	Methods in Molecular Biology
Publisher	Humana Press Inc.
Pages	171-189
Number of pages	19
DOIs	https://doi.org/10.1007/978-1-4939-3771-4_12
Publication status	Published - 2016

Publication series

Name	Methods in Molecular Biology
Volume	1451
ISSN (Print)	1064-3745

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media New York 2016.

ASJC Scopus Subject Areas

Molecular Biology
Genetics

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10.1007/978-1-4939-3771-4_12

Cite this

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title = "Modeling leukemogenesis in the Zebrafish using genetic and xenograftmodels",

abstract = "The zebrafish is a widely accepted model to study leukemia. The major advantage of studying leukemogenesis in zebrafish is attributed to its short life cycle and superior imaging capacity. This chapter highlights using transgenic-and xenograft-based models in zebrafish to study a specific leukemogenic mutation and analyze therapeutic responses in vivo.",

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AU - Dellaire, Graham

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AB - The zebrafish is a widely accepted model to study leukemia. The major advantage of studying leukemogenesis in zebrafish is attributed to its short life cycle and superior imaging capacity. This chapter highlights using transgenic-and xenograft-based models in zebrafish to study a specific leukemogenic mutation and analyze therapeutic responses in vivo.

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T3 - Methods in Molecular Biology

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BT - Methods in Molecular Biology

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Modeling leukemogenesis in the Zebrafish using genetic and xenograftmodels

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