Modeling leukemogenesis in the Zebrafish using genetic and xenograftmodels

Vinothkumar Rajan, Graham Dellaire, Jason N. Berman

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

The zebrafish is a widely accepted model to study leukemia. The major advantage of studying leukemogenesis in zebrafish is attributed to its short life cycle and superior imaging capacity. This chapter highlights using transgenic-and xenograft-based models in zebrafish to study a specific leukemogenic mutation and analyze therapeutic responses in vivo.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages171-189
Number of pages19
DOIs
Publication statusPublished - 2016

Publication series

NameMethods in Molecular Biology
Volume1451
ISSN (Print)1064-3745

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media New York 2016.

ASJC Scopus Subject Areas

  • Molecular Biology
  • Genetics

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