Abstract
The zebrafish is a widely accepted model to study leukemia. The major advantage of studying leukemogenesis in zebrafish is attributed to its short life cycle and superior imaging capacity. This chapter highlights using transgenic-and xenograft-based models in zebrafish to study a specific leukemogenic mutation and analyze therapeutic responses in vivo.
Original language | English |
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Title of host publication | Methods in Molecular Biology |
Publisher | Humana Press Inc. |
Pages | 171-189 |
Number of pages | 19 |
DOIs | |
Publication status | Published - 2016 |
Publication series
Name | Methods in Molecular Biology |
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Volume | 1451 |
ISSN (Print) | 1064-3745 |
Bibliographical note
Publisher Copyright:© Springer Science+Business Media New York 2016.
ASJC Scopus Subject Areas
- Molecular Biology
- Genetics
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Rajan, V., Dellaire, G., & Berman, J. N. (2016). Modeling leukemogenesis in the Zebrafish using genetic and xenograftmodels. In Methods in Molecular Biology (pp. 171-189). (Methods in Molecular Biology; Vol. 1451). Humana Press Inc.. https://doi.org/10.1007/978-1-4939-3771-4_12