Modeling leukemogenesis in the Zebrafish using genetic and xenograftmodels

Vinothkumar Rajan; Graham Dellaire; Jason N. Berman

doi:10.1007/978-1-4939-3771-4_12

Modeling leukemogenesis in the Zebrafish using genetic and xenograftmodels

Vinothkumar Rajan, Graham Dellaire, Jason N. Berman

Medicine

Résultat de recherche: Chapter

4 Citations (Scopus)

Résumé

The zebrafish is a widely accepted model to study leukemia. The major advantage of studying leukemogenesis in zebrafish is attributed to its short life cycle and superior imaging capacity. This chapter highlights using transgenic-and xenograft-based models in zebrafish to study a specific leukemogenic mutation and analyze therapeutic responses in vivo.

Langue d'origine	English
Titre de la publication principale	Methods in Molecular Biology
Maison d'édition	Humana Press Inc.
Pages	171-189
Nombre de pages	19
DOI	https://doi.org/10.1007/978-1-4939-3771-4_12
Statut de publication	Published - 2016

Séries de publication

Prénom	Methods in Molecular Biology
Volume	1451
ISSN (imprimé)	1064-3745

Note bibliographique

Publisher Copyright:
© Springer Science+Business Media New York 2016.

ASJC Scopus Subject Areas

Molecular Biology
Genetics

Accès au document

10.1007/978-1-4939-3771-4_12

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abstract = "The zebrafish is a widely accepted model to study leukemia. The major advantage of studying leukemogenesis in zebrafish is attributed to its short life cycle and superior imaging capacity. This chapter highlights using transgenic-and xenograft-based models in zebrafish to study a specific leukemogenic mutation and analyze therapeutic responses in vivo.",

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Modeling leukemogenesis in the Zebrafish using genetic and xenograftmodels

Résumé

Séries de publication

Note bibliographique

ASJC Scopus Subject Areas

Accès au document

Autres fichiers et liens

Empreinte numérique

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