Olfactory identification ability in pre- and postmenopausal women with schizophrenia

Lili C. Kopala, Kim Good, William G. Honer

Research output: Contribution to journalArticlepeer-review

47 Citations (Scopus)

Abstract

Previously we reported olfactory deficits in young male but not female patients with schizophrenia. In the present report, olfactory identification ability in pre- and postmenopausal women with schizophrenia and normal control subjects was assessed using the University of Pennsylvania Smell Identification Test (UPSIT). Additionally, serum estradiol levels were measured on the same 2 days as smell testing was completed. Olfactory deficits were observed in pre- and postmenopausal women with schizophrenia but were more pronounced in the postmenopausal patients. Regarding estradiol levels, women with schizophrenia had lower estradiol levels than did normal control subjects. The findings of this study indicate that olfactory deficits do exist in women with schizophrenia and may be accentuated by estrogen depletion.

Original languageEnglish
Pages (from-to)57-63
Number of pages7
JournalBiological Psychiatry
Volume38
Issue number1
DOIs
Publication statusPublished - Jul 1 1995
Externally publishedYes

Bibliographical note

Funding Information:
Dr. Kopala was supported by the British Columbia Health Care Research Foundation and Canadian Psychiatric Research Foundation. Dr. Honer received a scholarship from the Medical Research Council of Canada.

ASJC Scopus Subject Areas

  • Biological Psychiatry

PubMed: MeSH publication types

  • Comparative Study
  • Journal Article
  • Research Support, Non-U.S. Gov't

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