Olfactory identification ability in pre- and postmenopausal women with schizophrenia

Lili C. Kopala, Kim Good, William G. Honer

Résultat de recherche: Articleexamen par les pairs

47 Citations (Scopus)

Résumé

Previously we reported olfactory deficits in young male but not female patients with schizophrenia. In the present report, olfactory identification ability in pre- and postmenopausal women with schizophrenia and normal control subjects was assessed using the University of Pennsylvania Smell Identification Test (UPSIT). Additionally, serum estradiol levels were measured on the same 2 days as smell testing was completed. Olfactory deficits were observed in pre- and postmenopausal women with schizophrenia but were more pronounced in the postmenopausal patients. Regarding estradiol levels, women with schizophrenia had lower estradiol levels than did normal control subjects. The findings of this study indicate that olfactory deficits do exist in women with schizophrenia and may be accentuated by estrogen depletion.

Langue d'origineEnglish
Pages (de-à)57-63
Nombre de pages7
JournalBiological Psychiatry
Volume38
Numéro de publication1
DOI
Statut de publicationPublished - juill. 1 1995
Publié à l'externeOui

Note bibliographique

Funding Information:
Dr. Kopala was supported by the British Columbia Health Care Research Foundation and Canadian Psychiatric Research Foundation. Dr. Honer received a scholarship from the Medical Research Council of Canada.

ASJC Scopus Subject Areas

  • Biological Psychiatry

PubMed: MeSH publication types

  • Comparative Study
  • Journal Article
  • Research Support, Non-U.S. Gov't

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