Relationship between degree of histologic abnormality and serum alanine aminotransferase activity in experimental alcoholic liver disease

A. A. Nanji, S. W. French

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We studied the relationship between semi-quantitative estimates of liver damage and serum alanine aminotransferase (ALT) in our rat model for alcoholic liver disease. We found a significant correlation (r=0.79, p<0.01) between the histologic score for liver damage and serum ALT. Our results suggest that the serum activity of ALT is a useful guide to the estimation of liver pathology in experimental alcoholic liver disease.

Original languageEnglish
Pages (from-to)125-128
Number of pages4
JournalResearch Communications in Substances of Abuse
Volume9
Issue number2
Publication statusPublished - 1988
Externally publishedYes

ASJC Scopus Subject Areas

  • Medicine (miscellaneous)

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