Abstract
Age-related changes in sleep and circadian regulation occur as early as the middle years of life. Research also suggests that sleep and circadian rhythms are regulated differently between women and men. However, does sleep and circadian rhythms regulation age similarly in men and women? In this review, we present the mechanisms underlying age-related differences in sleep and the current state of knowledge on how they interact with sex. We also address how testosterone, estrogens, and progesterone fluctuations across adulthood interact with sleep and circadian regulation. Finally, we will propose research avenues to unravel the mechanisms underlying sex differences in age-related effects on sleep.
| Original language | English |
|---|---|
| Pages (from-to) | 66-85 |
| Number of pages | 20 |
| Journal | Frontiers in Neuroendocrinology |
| Volume | 47 |
| DOIs | |
| Publication status | Published - Oct 2017 |
Bibliographical note
Funding Information:The authors are grateful to Dominique Petit, Ph.D. for comments and revisions to the manuscript. Some of the work presented was supported by the Canadian Institutes of Health Research , the Natural Sciences and Engineering Research Council of Canada , and Dalhousie Medical Research Foundation . JC was support by a salary award from the Fonds de Recherche du Québec en Santé.
Funding Information:
The authors are grateful to Dominique Petit, Ph.D. for comments and revisions to the manuscript. Some of the work presented was supported by the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council of Canada, and Dalhousie Medical Research Foundation. JC was support by a salary award from the Fonds de Recherche du Qu?bec en Sant?.
Publisher Copyright:
© 2017 Elsevier Inc.
ASJC Scopus Subject Areas
- Endocrine and Autonomic Systems