Sex differences in age-related changes in the sleep-wake cycle

Julie Carrier, Kazue Semba, Samuel Deurveilher, Lauren Drogos, Jessica Cyr-Cronier, Catherine Lord, Zoran Sekerovick

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92 Citas (Scopus)

Resumen

Age-related changes in sleep and circadian regulation occur as early as the middle years of life. Research also suggests that sleep and circadian rhythms are regulated differently between women and men. However, does sleep and circadian rhythms regulation age similarly in men and women? In this review, we present the mechanisms underlying age-related differences in sleep and the current state of knowledge on how they interact with sex. We also address how testosterone, estrogens, and progesterone fluctuations across adulthood interact with sleep and circadian regulation. Finally, we will propose research avenues to unravel the mechanisms underlying sex differences in age-related effects on sleep.

Idioma originalEnglish
Páginas (desde-hasta)66-85
Número de páginas20
PublicaciónFrontiers in Neuroendocrinology
Volumen47
DOI
EstadoPublished - oct. 2017

Nota bibliográfica

Funding Information:
The authors are grateful to Dominique Petit, Ph.D. for comments and revisions to the manuscript. Some of the work presented was supported by the Canadian Institutes of Health Research , the Natural Sciences and Engineering Research Council of Canada , and Dalhousie Medical Research Foundation . JC was support by a salary award from the Fonds de Recherche du Québec en Santé.

Funding Information:
The authors are grateful to Dominique Petit, Ph.D. for comments and revisions to the manuscript. Some of the work presented was supported by the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council of Canada, and Dalhousie Medical Research Foundation. JC was support by a salary award from the Fonds de Recherche du Qu?bec en Sant?.

Publisher Copyright:
© 2017 Elsevier Inc.

ASJC Scopus Subject Areas

  • Endocrine and Autonomic Systems

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