TY - JOUR
T1 - Some neoplasms and some hamartomatous syndromes
T2 - Genetic considerations
AU - Cohen, M. Michael
PY - 1998/10
Y1 - 1998/10
N2 - This is the first of three articles on modern genetic concepts of a number of syndromes and disorders. About 1% of cancer mutations arise in the germline and produce a variety of neoplasms and hamartomatous syndromes. However, upward of 10-15% of all cancers have a major inherited component, although many of these are still enigmatic. The genetic basis is presented and following a review of many neoplasms and hamartomatous syndromes, the RET proto-oncogene is discussed as an example.
AB - This is the first of three articles on modern genetic concepts of a number of syndromes and disorders. About 1% of cancer mutations arise in the germline and produce a variety of neoplasms and hamartomatous syndromes. However, upward of 10-15% of all cancers have a major inherited component, although many of these are still enigmatic. The genetic basis is presented and following a review of many neoplasms and hamartomatous syndromes, the RET proto-oncogene is discussed as an example.
UR - http://www.scopus.com/inward/record.url?scp=0032185761&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032185761&partnerID=8YFLogxK
U2 - 10.1016/S0901-5027(98)80066-0
DO - 10.1016/S0901-5027(98)80066-0
M3 - Article
C2 - 9804200
AN - SCOPUS:0032185761
SN - 0901-5027
VL - 27
SP - 363
EP - 369
JO - International Journal of Oral and Maxillofacial Surgery
JF - International Journal of Oral and Maxillofacial Surgery
IS - 5
ER -
