Some neoplasms and some hamartomatous syndromes: Genetic considerations

M. Michael Cohen

doi:10.1016/S0901-5027(98)80066-0

Some neoplasms and some hamartomatous syndromes: Genetic considerations

M. Michael Cohen

Medicine

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10 Citations (Scopus)

Résumé

This is the first of three articles on modern genetic concepts of a number of syndromes and disorders. About 1% of cancer mutations arise in the germline and produce a variety of neoplasms and hamartomatous syndromes. However, upward of 10-15% of all cancers have a major inherited component, although many of these are still enigmatic. The genetic basis is presented and following a review of many neoplasms and hamartomatous syndromes, the RET proto-oncogene is discussed as an example.

Langue d'origine	English
Pages (de-à)	363-369
Nombre de pages	7
Journal	International Journal of Oral and Maxillofacial Surgery
Volume	27
Numéro de publication	5
DOI	https://doi.org/10.1016/S0901-5027(98)80066-0
Statut de publication	Published - oct. 1998

ASJC Scopus Subject Areas

Surgery
Oral Surgery
Otorhinolaryngology

ODD de l’ONU

Cette action contribue à la réalisation des objectifs de développement durable suivants

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10.1016/S0901-5027(98)80066-0

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AB - This is the first of three articles on modern genetic concepts of a number of syndromes and disorders. About 1% of cancer mutations arise in the germline and produce a variety of neoplasms and hamartomatous syndromes. However, upward of 10-15% of all cancers have a major inherited component, although many of these are still enigmatic. The genetic basis is presented and following a review of many neoplasms and hamartomatous syndromes, the RET proto-oncogene is discussed as an example.

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Some neoplasms and some hamartomatous syndromes: Genetic considerations

Résumé

ASJC Scopus Subject Areas

ODD de l’ONU

Accès au document

Autres fichiers et liens

Empreinte numérique

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