The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman

Sharon L. Mulvagh; Kerri Anne Mullen; Kara A. Nerenberg; Amy A. Kirkham; Courtney R. Green; Abida R. Dhukai; Jasmine Grewal; Marsha Hardy; Paula J. Harvey; Sofia B. Ahmed; Donna Hart; Anna L.E. Levinsson; Monica Parry; Heather J.A. Foulds; Christine Pacheco; Sandra M. Dumanski; Graeme Smith; Colleen M. Norris

doi:10.1016/j.cjco.2021.09.013

The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman

Sharon L. Mulvagh, Kerri Anne Mullen, Kara A. Nerenberg, Amy A. Kirkham, Courtney R. Green, Abida R. Dhukai, Jasmine Grewal, Marsha Hardy, Paula J. Harvey, Sofia B. Ahmed, Donna Hart, Anna L.E. Levinsson, Monica Parry, Heather J.A. Foulds, Christine Pacheco, Sandra M. Dumanski, Graeme Smith, Colleen M. Norris

Medicine

Research output: Contribution to journal › Review article › peer-review

37 Citations (Scopus)

Abstract

Women have unique sex- and gender-related risk factors for cardiovascular disease (CVD) that can present or evolve over their lifespan. Pregnancy-associated conditions, polycystic ovarian syndrome, and menopause can increase a woman's risk of CVD. Women are at greater risk for autoimmune rheumatic disorders, which play a role in the predisposition and pathogenesis of CVD. The influence of traditional CVD risk factors (eg, smoking, hypertension, diabetes, obesity, physical inactivity, depression, anxiety, and family history) is greater in women than men. Finally, there are sex differences in the response to treatments for CVD risk and comorbid disease processes. In this Atlas chapter we review sex- and gender-unique CVD risk factors that can occur across a woman's lifespan, with the aim to reduce knowledge gaps and guide the development of optimal strategies for awareness and treatment.

Original language	English
Pages (from-to)	115-132
Number of pages	18
Journal	CJC Open
Volume	4
Issue number	2
DOIs	https://doi.org/10.1016/j.cjco.2021.09.013
Publication status	Published - Feb 2022

Bibliographical note

Funding Information:
The authors gratefully acknowledge Lisa Comber for her ongoing coordination of this Atlas. A special thanks goes to Alexa Desjarlais from the University of Calgary and Manu Sandhu and Angela Poitras from the University of Ottawa Heart Institute for their graphic design of the central chapter illustration. Thanks to Manu Sandhu for graphic design of Figure 2. This article has been submitted on behalf of the CWHHA, a pan-Canadian network of approximately 100 clinicians, scientists, allied health professionals, program administrators, and patient partners, whose aim is to develop and disseminate evidence-informed strategies to transform clinical practice and enhance collaborative action on women's CV health in Canada. The CWHHA is powered by the Canadian Women's Heart Health Centre at the University of Ottawa Heart Institute. Supported by the University of Ottawa Heart Institute Foundation. S.L.M. is a member of the Novo Nordisk SOUL trial steering committee. A.L.E.L. has received grants from Astra Zeneca. The remaining authors have no conflicts of interest to disclose.

Publisher Copyright:
© 2021 The Authors

ASJC Scopus Subject Areas

Cardiology and Cardiovascular Medicine

PubMed: MeSH publication types

Journal Article
Review

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.cjco.2021.09.013

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Mulvagh, S. L., Mullen, K. A., Nerenberg, K. A., Kirkham, A. A., Green, C. R., Dhukai, A. R., Grewal, J., Hardy, M., Harvey, P. J., Ahmed, S. B., Hart, D., Levinsson, A. L. E., Parry, M., Foulds, H. J. A., Pacheco, C., Dumanski, S. M., Smith, G., & Norris, C. M. (2022). The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman. CJC Open, 4(2), 115-132. https://doi.org/10.1016/j.cjco.2021.09.013

The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman. / Mulvagh, Sharon L.; Mullen, Kerri Anne; Nerenberg, Kara A. et al.
In: CJC Open, Vol. 4, No. 2, 02.2022, p. 115-132.

Research output: Contribution to journal › Review article › peer-review

Mulvagh, SL, Mullen, KA, Nerenberg, KA, Kirkham, AA, Green, CR, Dhukai, AR, Grewal, J, Hardy, M, Harvey, PJ, Ahmed, SB, Hart, D, Levinsson, ALE, Parry, M, Foulds, HJA, Pacheco, C, Dumanski, SM, Smith, G & Norris, CM 2022, 'The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman', CJC Open, vol. 4, no. 2, pp. 115-132. https://doi.org/10.1016/j.cjco.2021.09.013

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note = "Funding Information: The authors gratefully acknowledge Lisa Comber for her ongoing coordination of this Atlas. A special thanks goes to Alexa Desjarlais from the University of Calgary and Manu Sandhu and Angela Poitras from the University of Ottawa Heart Institute for their graphic design of the central chapter illustration. Thanks to Manu Sandhu for graphic design of Figure 2. This article has been submitted on behalf of the CWHHA, a pan-Canadian network of approximately 100 clinicians, scientists, allied health professionals, program administrators, and patient partners, whose aim is to develop and disseminate evidence-informed strategies to transform clinical practice and enhance collaborative action on women's CV health in Canada. The CWHHA is powered by the Canadian Women's Heart Health Centre at the University of Ottawa Heart Institute. Supported by the University of Ottawa Heart Institute Foundation. S.L.M. is a member of the Novo Nordisk SOUL trial steering committee. A.L.E.L. has received grants from Astra Zeneca. The remaining authors have no conflicts of interest to disclose. Publisher Copyright: {\textcopyright} 2021 The Authors",

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The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman

Abstract

Bibliographical note

ASJC Scopus Subject Areas

PubMed: MeSH publication types

UN SDGs

Access to Document

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Cite this