The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman

Sharon L. Mulvagh, Kerri Anne Mullen, Kara A. Nerenberg, Amy A. Kirkham, Courtney R. Green, Abida R. Dhukai, Jasmine Grewal, Marsha Hardy, Paula J. Harvey, Sofia B. Ahmed, Donna Hart, Anna L.E. Levinsson, Monica Parry, Heather J.A. Foulds, Christine Pacheco, Sandra M. Dumanski, Graeme Smith, Colleen M. Norris

Résultat de recherche: Review articleexamen par les pairs

33 Citations (Scopus)

Résumé

Women have unique sex- and gender-related risk factors for cardiovascular disease (CVD) that can present or evolve over their lifespan. Pregnancy-associated conditions, polycystic ovarian syndrome, and menopause can increase a woman's risk of CVD. Women are at greater risk for autoimmune rheumatic disorders, which play a role in the predisposition and pathogenesis of CVD. The influence of traditional CVD risk factors (eg, smoking, hypertension, diabetes, obesity, physical inactivity, depression, anxiety, and family history) is greater in women than men. Finally, there are sex differences in the response to treatments for CVD risk and comorbid disease processes. In this Atlas chapter we review sex- and gender-unique CVD risk factors that can occur across a woman's lifespan, with the aim to reduce knowledge gaps and guide the development of optimal strategies for awareness and treatment.

Langue d'origineEnglish
Pages (de-à)115-132
Nombre de pages18
JournalCJC Open
Volume4
Numéro de publication2
DOI
Statut de publicationPublished - févr. 2022

Note bibliographique

Funding Information:
The authors gratefully acknowledge Lisa Comber for her ongoing coordination of this Atlas. A special thanks goes to Alexa Desjarlais from the University of Calgary and Manu Sandhu and Angela Poitras from the University of Ottawa Heart Institute for their graphic design of the central chapter illustration. Thanks to Manu Sandhu for graphic design of Figure 2. This article has been submitted on behalf of the CWHHA, a pan-Canadian network of approximately 100 clinicians, scientists, allied health professionals, program administrators, and patient partners, whose aim is to develop and disseminate evidence-informed strategies to transform clinical practice and enhance collaborative action on women's CV health in Canada. The CWHHA is powered by the Canadian Women's Heart Health Centre at the University of Ottawa Heart Institute. Supported by the University of Ottawa Heart Institute Foundation. S.L.M. is a member of the Novo Nordisk SOUL trial steering committee. A.L.E.L. has received grants from Astra Zeneca. The remaining authors have no conflicts of interest to disclose.

Publisher Copyright:
© 2021 The Authors

ASJC Scopus Subject Areas

  • Cardiology and Cardiovascular Medicine

PubMed: MeSH publication types

  • Journal Article
  • Review

Empreinte numérique

Plonger dans les sujets de recherche 'The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman'. Ensemble, ils forment une empreinte numérique unique.

Citer