The effect of synthetic oxytocin on impaired atrioventricular conduction

Gerald A. Klassen; Joseph W. Rubin; Maurice McGregor

doi:10.1016/0002-9149(63)90191-7

The effect of synthetic oxytocin on impaired atrioventricular conduction

Gerald A. Klassen, Joseph W. Rubin, Maurice McGregor

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

It has been shown that synthetic oxytocin has the ability to promote A-V conduction under various experimental and clinical circumstances: (1) when A-V block is induced by anoxia or noradrenalin administration in the isolated heart; (2) when A-V block is induced by digitalis toxicity in the intact cat; (3) in certain forms of clinical heart block in man; and (4) in intact man with atrial fibrillation under digitalis therapy. This effect is transient and appears to be a direct action on the heart itself.

Original language	English
Pages (from-to)	523-526
Number of pages	4
Journal	American Journal of Cardiology
Volume	12
Issue number	4
DOIs	https://doi.org/10.1016/0002-9149(63)90191-7
Publication status	Published - Oct 1963
Externally published	Yes

Bibliographical note

Funding Information:
RESULTS Isolated Cat Heart: The effect of oxytocin on complete heart block was tested in 14 isolated * From the Joint Cardio-Respiratory Service of the Royal Victoria Hospital and the Montreal Children’s Hospital, Montreal, Quebec, Canada. This study was supported by a grant from the John A. Hartford Foundation.

ASJC Scopus Subject Areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1016/0002-9149(63)90191-7

Cite this

@article{56f89ca34aed4f038029cce773abd5fb,

title = "The effect of synthetic oxytocin on impaired atrioventricular conduction",

abstract = "It has been shown that synthetic oxytocin has the ability to promote A-V conduction under various experimental and clinical circumstances: (1) when A-V block is induced by anoxia or noradrenalin administration in the isolated heart; (2) when A-V block is induced by digitalis toxicity in the intact cat; (3) in certain forms of clinical heart block in man; and (4) in intact man with atrial fibrillation under digitalis therapy. This effect is transient and appears to be a direct action on the heart itself.",

author = "Klassen, {Gerald A.} and Rubin, {Joseph W.} and Maurice McGregor",

note = "Funding Information: RESULTS Isolated Cat Heart: The effect of oxytocin on complete heart block was tested in 14 isolated * From the Joint Cardio-Respiratory Service of the Royal Victoria Hospital and the Montreal Children{\textquoteright}s Hospital, Montreal, Quebec, Canada. This study was supported by a grant from the John A. Hartford Foundation.",

year = "1963",

month = oct,

doi = "10.1016/0002-9149(63)90191-7",

language = "English",

volume = "12",

pages = "523--526",

journal = "American Journal of Cardiology",

issn = "0002-9149",

publisher = "Elsevier Inc.",

number = "4",

}

TY - JOUR

T1 - The effect of synthetic oxytocin on impaired atrioventricular conduction

AU - Klassen, Gerald A.

AU - Rubin, Joseph W.

AU - McGregor, Maurice

N1 - Funding Information: RESULTS Isolated Cat Heart: The effect of oxytocin on complete heart block was tested in 14 isolated * From the Joint Cardio-Respiratory Service of the Royal Victoria Hospital and the Montreal Children’s Hospital, Montreal, Quebec, Canada. This study was supported by a grant from the John A. Hartford Foundation.

PY - 1963/10

Y1 - 1963/10

N2 - It has been shown that synthetic oxytocin has the ability to promote A-V conduction under various experimental and clinical circumstances: (1) when A-V block is induced by anoxia or noradrenalin administration in the isolated heart; (2) when A-V block is induced by digitalis toxicity in the intact cat; (3) in certain forms of clinical heart block in man; and (4) in intact man with atrial fibrillation under digitalis therapy. This effect is transient and appears to be a direct action on the heart itself.

AB - It has been shown that synthetic oxytocin has the ability to promote A-V conduction under various experimental and clinical circumstances: (1) when A-V block is induced by anoxia or noradrenalin administration in the isolated heart; (2) when A-V block is induced by digitalis toxicity in the intact cat; (3) in certain forms of clinical heart block in man; and (4) in intact man with atrial fibrillation under digitalis therapy. This effect is transient and appears to be a direct action on the heart itself.

UR - http://www.scopus.com/inward/record.url?scp=44649085481&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=44649085481&partnerID=8YFLogxK

U2 - 10.1016/0002-9149(63)90191-7

DO - 10.1016/0002-9149(63)90191-7

M3 - Article

C2 - 14067434

AN - SCOPUS:44649085481

SN - 0002-9149

VL - 12

SP - 523

EP - 526

JO - American Journal of Cardiology

JF - American Journal of Cardiology

IS - 4

ER -

The effect of synthetic oxytocin on impaired atrioventricular conduction

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this