The Origins and Early History of Polydnavirus Research

Don Stoltz; Peter Krell

doi:10.1016/B978-0-12-384858-1.00001-1

The Origins and Early History of Polydnavirus Research

Don Stoltz, Peter Krell

Medicine

Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Citations (Scopus)

Abstract

This chapter traces the origins and early history of polydnavirus (PDV) research, linking that to recent progress in the field. It identifies some of the important milestones in PDV research, nonetheless recognizing the inherently subjective nature of any such enterprise. It makes no attempt to provide a comprehensive coverage of events and does not deal with literature describing the effects of PDVs (and/or wasp venoms) on host physiology. PDVs were incapable of replicating in the parasitized host and of course this made sense: a replicative virus might also be a pathogenic virus, with potentially dire consequence for the developing endoparasitoid. The early work from the Summers lab described virus-specific transcriptional activity in various host tissues, it was clear that this was occurring in the apparent absence of viral DNA synthesis; accordingly, the assumption made was that viral replication was necessarily abortive, for the reason already given.

Original language	English
Title of host publication	Parasitoid Viruses
Subtitle of host publication	Symbionts and Pathogens
Publisher	Elsevier Inc.
Pages	5-13
Number of pages	9
ISBN (Print)	9780123848581
DOIs	https://doi.org/10.1016/B978-0-12-384858-1.00001-1
Publication status	Published - 2012

Bibliographical note

Funding Information:
DBS wishes to acknowledge the many invaluable contributions made over the years by his students and technicians, many of whom worked above and beyond the call of duty; among these is included the incomparable Aricy Pan, whose efforts have been received with both gratitude and affection. In addition, he thanks the PDV community in general for its unwavering enthusiam, support, and collegiality. Research in his lab has been supported by the then Medical and National Research Councils and, more recently, by the Natural Sciences and Engineering Research Council of Canada. PJK is also pleased to acknowledge support from the latter agency, as well as support from Max Summers and Brad Vinson during his postdoctoral days at TAMU.

ASJC Scopus Subject Areas

General Biochemistry,Genetics and Molecular Biology

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10.1016/B978-0-12-384858-1.00001-1

Cite this

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The Origins and Early History of Polydnavirus Research

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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