The Origins and Early History of Polydnavirus Research

Don Stoltz, Peter Krell

Producción científica: Capítulo en Libro/Reporte/Acta de conferenciaCapítulo

5 Citas (Scopus)

Resumen

This chapter traces the origins and early history of polydnavirus (PDV) research, linking that to recent progress in the field. It identifies some of the important milestones in PDV research, nonetheless recognizing the inherently subjective nature of any such enterprise. It makes no attempt to provide a comprehensive coverage of events and does not deal with literature describing the effects of PDVs (and/or wasp venoms) on host physiology. PDVs were incapable of replicating in the parasitized host and of course this made sense: a replicative virus might also be a pathogenic virus, with potentially dire consequence for the developing endoparasitoid. The early work from the Summers lab described virus-specific transcriptional activity in various host tissues, it was clear that this was occurring in the apparent absence of viral DNA synthesis; accordingly, the assumption made was that viral replication was necessarily abortive, for the reason already given.

Idioma originalEnglish
Título de la publicación alojadaParasitoid Viruses
Subtítulo de la publicación alojadaSymbionts and Pathogens
EditorialElsevier Inc.
Páginas5-13
Número de páginas9
ISBN (versión impresa)9780123848581
DOI
EstadoPublished - 2012

Nota bibliográfica

Funding Information:
DBS wishes to acknowledge the many invaluable contributions made over the years by his students and technicians, many of whom worked above and beyond the call of duty; among these is included the incomparable Aricy Pan, whose efforts have been received with both gratitude and affection. In addition, he thanks the PDV community in general for its unwavering enthusiam, support, and collegiality. Research in his lab has been supported by the then Medical and National Research Councils and, more recently, by the Natural Sciences and Engineering Research Council of Canada. PJK is also pleased to acknowledge support from the latter agency, as well as support from Max Summers and Brad Vinson during his postdoctoral days at TAMU.

ASJC Scopus Subject Areas

  • General Biochemistry,Genetics and Molecular Biology

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