Detection of a novel t(6;15)(q21;q21) in a pediatric Wilms tumor

Conrad V. Fernandez; Valia S. Lestou; Julia Wildish; Christine L.Y. Lee; Poul H.B. Sorensen

doi:10.1016/S0165-4608(01)00445-9

Detection of a novel t(6;15)(q21;q21) in a pediatric Wilms tumor

Conrad V. Fernandez, Valia S. Lestou, Julia Wildish, Christine L.Y. Lee, Poul H.B. Sorensen

Medicine

Medicine

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10 Citas (Scopus)

Resumen

We report a novel cytogenetic finding in a favorable histology Wilms tumor occurring in a 4-month-old boy. Karyotypic analysis demonstrated a t(6;15)(q21;q21) in all tumor cells examined. This was confirmed using fluorescence in situ hybridization analysis. Molecular analysis of this rearrangement may provide clues to understanding the pathobiology of Wilms tumor.

Idioma original	English
Páginas (desde-hasta)	165-167
Número de páginas	3
Publicación	Cancer Genetics and Cytogenetics
Volumen	129
N.º	2
DOI	https://doi.org/10.1016/S0165-4608(01)00445-9
Estado	Published - 2001

ASJC Scopus Subject Areas

Molecular Biology
Genetics
Cancer Research

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abstract = "We report a novel cytogenetic finding in a favorable histology Wilms tumor occurring in a 4-month-old boy. Karyotypic analysis demonstrated a t(6;15)(q21;q21) in all tumor cells examined. This was confirmed using fluorescence in situ hybridization analysis. Molecular analysis of this rearrangement may provide clues to understanding the pathobiology of Wilms tumor.",

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AU - Fernandez, Conrad V.

AU - Lestou, Valia S.

AU - Wildish, Julia

AU - Lee, Christine L.Y.

AU - Sorensen, Poul H.B.

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AB - We report a novel cytogenetic finding in a favorable histology Wilms tumor occurring in a 4-month-old boy. Karyotypic analysis demonstrated a t(6;15)(q21;q21) in all tumor cells examined. This was confirmed using fluorescence in situ hybridization analysis. Molecular analysis of this rearrangement may provide clues to understanding the pathobiology of Wilms tumor.

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Detection of a novel t(6;15)(q21;q21) in a pediatric Wilms tumor

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