Effects of perhexiline maleate on coronary flow distribution in the ischemic canine myocardium

G. A. Klassen; F. Sestier; A. L'Abbate; R. R. Mildenberger; D. T. Zborowska-Sluis

doi:10.1161/01.CIR.54.1.14

Effects of perhexiline maleate on coronary flow distribution in the ischemic canine myocardium

G. A. Klassen, F. Sestier, A. L'Abbate, R. R. Mildenberger, D. T. Zborowska-Sluis

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

11 Citas (Scopus)

Resumen

Intravenous perhexilline maleate in a canine preparation with fixed coronary flow increases coronary diastolic pressure. It also redistributed coronary flow so as to preserve endocardial flow. Myocardial oxygen consumption was reduced and lactate uptake enhanced by the drug. It had no effect upon the threshold for ischemic induced left ventricular failure.

Idioma original	English
Páginas (desde-hasta)	14-20
Número de páginas	7
Publicación	Unknown Journal
Volumen	54
N.º	1
DOI	https://doi.org/10.1161/01.CIR.54.1.14
Estado	Published - 1976
Publicado de forma externa	Sí

ASJC Scopus Subject Areas

Cardiology and Cardiovascular Medicine
Physiology (medical)

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10.1161/01.CIR.54.1.14

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abstract = "Intravenous perhexilline maleate in a canine preparation with fixed coronary flow increases coronary diastolic pressure. It also redistributed coronary flow so as to preserve endocardial flow. Myocardial oxygen consumption was reduced and lactate uptake enhanced by the drug. It had no effect upon the threshold for ischemic induced left ventricular failure.",

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AU - Sestier, F.

AU - L'Abbate, A.

AU - Mildenberger, R. R.

AU - Zborowska-Sluis, D. T.

PY - 1976

Y1 - 1976

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Effects of perhexiline maleate on coronary flow distribution in the ischemic canine myocardium

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