Evidence of carbonic anhydrase activity in skeletal muscle: A role for facilitative carbon dioxide transport

Danuta T. Zborowska-Sluis; Antonio L'Abbate; Gerald A. Klassen

doi:10.1016/0034-5687(74)90064-4

Evidence of carbonic anhydrase activity in skeletal muscle: A role for facilitative carbon dioxide transport

Danuta T. Zborowska-Sluis, Antonio L'Abbate, Gerald A. Klassen

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

21 Citas (Scopus)

Resumen

Carbon dioxide, water and vascular space were measured in the hind limb of the dog, with blood and plasma perfusion, before and after the administration of acetazolamide. Inhibition of carbonic anhydrase by acetazolamide resulted in a decrease in carbon dioxide space from greater than water space to similar to vascular space. This observation is consistent with the presence of carbonic anhydrase in the extravascular compartment. Its presence in this location could act to facilitate carbon dioxide transport.

Idioma original	English
Páginas (desde-hasta)	341-350
Número de páginas	10
Publicación	Respiration Physiology
Volumen	21
N.º	3
DOI	https://doi.org/10.1016/0034-5687(74)90064-4
Estado	Published - sep. 1974
Publicado de forma externa	Sí

Nota bibliográfica

Funding Information:
1 Supported by grants from the Medical Research Council and the Joseph Edwards ’ Supported by a grant from the Consiglio Nazionale delle Ricerche, Rome, Italy.

ASJC Scopus Subject Areas

Physiology
Pulmonary and Respiratory Medicine

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title = "Evidence of carbonic anhydrase activity in skeletal muscle: A role for facilitative carbon dioxide transport",

abstract = "Carbon dioxide, water and vascular space were measured in the hind limb of the dog, with blood and plasma perfusion, before and after the administration of acetazolamide. Inhibition of carbonic anhydrase by acetazolamide resulted in a decrease in carbon dioxide space from greater than water space to similar to vascular space. This observation is consistent with the presence of carbonic anhydrase in the extravascular compartment. Its presence in this location could act to facilitate carbon dioxide transport.",

author = "Zborowska-Sluis, {Danuta T.} and Antonio L'Abbate and Klassen, {Gerald A.}",

note = "Funding Information: 1 Supported by grants from the Medical Research Council and the Joseph Edwards {\textquoteright} Supported by a grant from the Consiglio Nazionale delle Ricerche, Rome, Italy.",

year = "1974",

month = sep,

doi = "10.1016/0034-5687(74)90064-4",

language = "English",

volume = "21",

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T2 - A role for facilitative carbon dioxide transport

AU - Zborowska-Sluis, Danuta T.

AU - L'Abbate, Antonio

AU - Klassen, Gerald A.

N1 - Funding Information: 1 Supported by grants from the Medical Research Council and the Joseph Edwards ’ Supported by a grant from the Consiglio Nazionale delle Ricerche, Rome, Italy.

PY - 1974/9

Y1 - 1974/9

N2 - Carbon dioxide, water and vascular space were measured in the hind limb of the dog, with blood and plasma perfusion, before and after the administration of acetazolamide. Inhibition of carbonic anhydrase by acetazolamide resulted in a decrease in carbon dioxide space from greater than water space to similar to vascular space. This observation is consistent with the presence of carbonic anhydrase in the extravascular compartment. Its presence in this location could act to facilitate carbon dioxide transport.

AB - Carbon dioxide, water and vascular space were measured in the hind limb of the dog, with blood and plasma perfusion, before and after the administration of acetazolamide. Inhibition of carbonic anhydrase by acetazolamide resulted in a decrease in carbon dioxide space from greater than water space to similar to vascular space. This observation is consistent with the presence of carbonic anhydrase in the extravascular compartment. Its presence in this location could act to facilitate carbon dioxide transport.

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U2 - 10.1016/0034-5687(74)90064-4

DO - 10.1016/0034-5687(74)90064-4

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VL - 21

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EP - 350

JO - Respiration Physiology

JF - Respiration Physiology

IS - 3

ER -

Evidence of carbonic anhydrase activity in skeletal muscle: A role for facilitative carbon dioxide transport

Resumen

Nota bibliográfica

ASJC Scopus Subject Areas

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Huella

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