Iron chelation for the treatment of uveitis

Junru Chen; Juan Zhou; Mel Kelly; Bruce E. Holbein; Christian Lehmann

doi:10.1016/j.mehy.2017.03.029

Iron chelation for the treatment of uveitis

Junru Chen, Juan Zhou, Mel Kelly, Bruce E. Holbein, Christian Lehmann

Medicine

Medicine

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

6 Citas (Scopus)

Resumen

Inflammatory eye diseases such as uveitis are common and may eventually result in vision loss. Iron can play a critical role in ocular inflammation via promoting the generation of oxygen free radicals and it is also nutritionally essential for microbial growth. Considering this involvement of iron in inflammation and microbial infection, we hypothesize that administration of iron chelators has potential to function as a novel therapy in uveitis and help improve clinical outcomes.

Idioma original	English
Páginas (desde-hasta)	1-4
Número de páginas	4
Publicación	Medical Hypotheses
Volumen	103
DOI	https://doi.org/10.1016/j.mehy.2017.03.029
Estado	Published - jun. 1 2017

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© 2017 Elsevier Ltd

ASJC Scopus Subject Areas

General Medicine

PubMed: MeSH publication types

Journal Article

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abstract = "Inflammatory eye diseases such as uveitis are common and may eventually result in vision loss. Iron can play a critical role in ocular inflammation via promoting the generation of oxygen free radicals and it is also nutritionally essential for microbial growth. Considering this involvement of iron in inflammation and microbial infection, we hypothesize that administration of iron chelators has potential to function as a novel therapy in uveitis and help improve clinical outcomes.",

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AU - Lehmann, Christian

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Iron chelation for the treatment of uveitis

Resumen

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