Lipids of Crithidia fasciculata. The occurrence and turnover of phosphoinositides

F. B.St C. Palmer

doi:10.1016/0005-2760(73)90070-2

Lipids of Crithidia fasciculata. The occurrence and turnover of phosphoinositides

F. B.St C. Palmer

Medicine

Medicine

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

19 Citas (Scopus)

Resumen

The lipids of Crithidia fasciculata have been analysed. In addition to phosphatidylcholine, phosphatidylinositol and phosphatidylethanolamine both diphosphoinositide and triphosphoinositide were identified. Plasmalogens, lysophosphatides, phosphatidylserine and phosphonolipids were absent. Experiments with ³²P_i as precursor indicated that only the phosphoinositides were formed at a rate appreciably greater than that necessary to sustain new growth. The turnover of the polyphosphoinositides was very rapid and they were quantitatively decreased in cells at the end of the logarithmic phase of growth.

Idioma original	English
Páginas (desde-hasta)	296-304
Número de páginas	9
Publicación	Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Volumen	316
N.º	3
DOI	https://doi.org/10.1016/0005-2760(73)90070-2
Estado	Published - sep. 25 1973

Nota bibliográfica

Funding Information:
This investigationw as supportedb y a grant from the Medical Research Council of Canada.T he technicala ssistanceo f Mrs M. F. Cameron and Miss L. Saulnieri s gratefullya cknowledged.

ASJC Scopus Subject Areas

Biophysics
Biochemistry
Endocrinology

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abstract = "The lipids of Crithidia fasciculata have been analysed. In addition to phosphatidylcholine, phosphatidylinositol and phosphatidylethanolamine both diphosphoinositide and triphosphoinositide were identified. Plasmalogens, lysophosphatides, phosphatidylserine and phosphonolipids were absent. Experiments with 32Pi as precursor indicated that only the phosphoinositides were formed at a rate appreciably greater than that necessary to sustain new growth. The turnover of the polyphosphoinositides was very rapid and they were quantitatively decreased in cells at the end of the logarithmic phase of growth.",

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AU - Palmer, F. B.St C.

N1 - Funding Information: This investigationw as supportedb y a grant from the Medical Research Council of Canada.T he technicala ssistanceo f Mrs M. F. Cameron and Miss L. Saulnieri s gratefullya cknowledged.

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Y1 - 1973/9/25

N2 - The lipids of Crithidia fasciculata have been analysed. In addition to phosphatidylcholine, phosphatidylinositol and phosphatidylethanolamine both diphosphoinositide and triphosphoinositide were identified. Plasmalogens, lysophosphatides, phosphatidylserine and phosphonolipids were absent. Experiments with 32Pi as precursor indicated that only the phosphoinositides were formed at a rate appreciably greater than that necessary to sustain new growth. The turnover of the polyphosphoinositides was very rapid and they were quantitatively decreased in cells at the end of the logarithmic phase of growth.

AB - The lipids of Crithidia fasciculata have been analysed. In addition to phosphatidylcholine, phosphatidylinositol and phosphatidylethanolamine both diphosphoinositide and triphosphoinositide were identified. Plasmalogens, lysophosphatides, phosphatidylserine and phosphonolipids were absent. Experiments with 32Pi as precursor indicated that only the phosphoinositides were formed at a rate appreciably greater than that necessary to sustain new growth. The turnover of the polyphosphoinositides was very rapid and they were quantitatively decreased in cells at the end of the logarithmic phase of growth.

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Lipids of Crithidia fasciculata. The occurrence and turnover of phosphoinositides

Resumen

Nota bibliográfica

ASJC Scopus Subject Areas

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