Lipids of Crithidia fasciculata. The occurrence and turnover of phosphoinositides

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Résumé

The lipids of Crithidia fasciculata have been analysed. In addition to phosphatidylcholine, phosphatidylinositol and phosphatidylethanolamine both diphosphoinositide and triphosphoinositide were identified. Plasmalogens, lysophosphatides, phosphatidylserine and phosphonolipids were absent. Experiments with 32Pi as precursor indicated that only the phosphoinositides were formed at a rate appreciably greater than that necessary to sustain new growth. The turnover of the polyphosphoinositides was very rapid and they were quantitatively decreased in cells at the end of the logarithmic phase of growth.

Langue d'origineEnglish
Pages (de-à)296-304
Nombre de pages9
JournalBiochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
Volume316
Numéro de publication3
DOI
Statut de publicationPublished - sept. 25 1973

Note bibliographique

Funding Information:
This investigationw as supportedb y a grant from the Medical Research Council of Canada.T he technicala ssistanceo f Mrs M. F. Cameron and Miss L. Saulnieri s gratefullya cknowledged.

ASJC Scopus Subject Areas

  • Biophysics
  • Biochemistry
  • Endocrinology

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