Resumen
We present the design, implementation and validation of a swept-source optical coherence tomography (OCT) system for real-time imaging of the human middle ear in live patients. Our system consists of a highly phase-stable Vernier-tuned distributed Bragg-reflector laser along with a real-time processing engine implemented on a graphics processing unit. We use the system to demonstrate, for the first time in live subjects, real-time Doppler measurements of middle ear vibration in response to sound, video rate 2D B-mode imaging of the middle ear and 3D volumetric B-mode imaging. All measurements were performed non-invasively through the intact tympanic membrane demonstrating that the technology is readily translatable to the clinic.
Idioma original | English |
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Número de artículo | #268551 |
Páginas (desde-hasta) | 4621-4635 |
Número de páginas | 15 |
Publicación | Biomedical Optics Express |
Volumen | 7 |
N.º | 11 |
DOI | |
Estado | Published - nov. 1 2016 |
Nota bibliográfica
Funding Information:This work was supported through grants from the Natural Sciences and Engineering Research Council of Canada, the Atlantic Canada Opportunities Agency, Springboard Atlantic and Innovacorp.
Publisher Copyright:
© 2016 Optical Society of America.
ASJC Scopus Subject Areas
- Biotechnology
- Atomic and Molecular Physics, and Optics