Prolonged depression of pelvic ganglion transmission - a peripheral manifestation of spinal cord transection

Devany A.S. Twiddy; John W. Downie; Said A. Awad

doi:10.1016/0006-8993(82)90026-9

Prolonged depression of pelvic ganglion transmission - a peripheral manifestation of spinal cord transection

Devany A.S. Twiddy, John W. Downie, Said A. Awad

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

Resumen

Spinal cord transection depressed the bladder's contractile response to pelvic nerve stimulation. This depression was prevented by prior hypogastric nerve section or guanethidine treatment, but was not reversed by the same treatments used after spinal transection. Thus the depression has a peripheral sympathetic basis but is not dependent on ongoing sympathetic nerve activity. Since responses to intra-arterial acetylcholine and dimethylphenylpiperazinium were unchanged by spinal transection, the depression of the pelvic nerve response probably occurs at a ganglion site.

Idioma original	English
Páginas (desde-hasta)	235-239
Número de páginas	5
Publicación	Brain Research
Volumen	231
N.º	1
DOI	https://doi.org/10.1016/0006-8993(82)90026-9
Estado	Published - ene. 7 1982
Publicado de forma externa	Sí

Nota bibliográfica

Funding Information:
Supported by the Medical Research Council of Canada. Dr. Twiddy was a recipient of a Multiple Sclerosis Society of Canada Research Studentship.

ASJC Scopus Subject Areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

PubMed: MeSH publication types

Journal Article
Research Support, Non-U.S. Gov't

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10.1016/0006-8993(82)90026-9

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title = "Prolonged depression of pelvic ganglion transmission - a peripheral manifestation of spinal cord transection",

abstract = "Spinal cord transection depressed the bladder's contractile response to pelvic nerve stimulation. This depression was prevented by prior hypogastric nerve section or guanethidine treatment, but was not reversed by the same treatments used after spinal transection. Thus the depression has a peripheral sympathetic basis but is not dependent on ongoing sympathetic nerve activity. Since responses to intra-arterial acetylcholine and dimethylphenylpiperazinium were unchanged by spinal transection, the depression of the pelvic nerve response probably occurs at a ganglion site.",

author = "Twiddy, {Devany A.S.} and Downie, {John W.} and Awad, {Said A.}",

note = "Funding Information: Supported by the Medical Research Council of Canada. Dr. Twiddy was a recipient of a Multiple Sclerosis Society of Canada Research Studentship.",

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AU - Downie, John W.

AU - Awad, Said A.

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PY - 1982/1/7

Y1 - 1982/1/7

N2 - Spinal cord transection depressed the bladder's contractile response to pelvic nerve stimulation. This depression was prevented by prior hypogastric nerve section or guanethidine treatment, but was not reversed by the same treatments used after spinal transection. Thus the depression has a peripheral sympathetic basis but is not dependent on ongoing sympathetic nerve activity. Since responses to intra-arterial acetylcholine and dimethylphenylpiperazinium were unchanged by spinal transection, the depression of the pelvic nerve response probably occurs at a ganglion site.

AB - Spinal cord transection depressed the bladder's contractile response to pelvic nerve stimulation. This depression was prevented by prior hypogastric nerve section or guanethidine treatment, but was not reversed by the same treatments used after spinal transection. Thus the depression has a peripheral sympathetic basis but is not dependent on ongoing sympathetic nerve activity. Since responses to intra-arterial acetylcholine and dimethylphenylpiperazinium were unchanged by spinal transection, the depression of the pelvic nerve response probably occurs at a ganglion site.

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Prolonged depression of pelvic ganglion transmission - a peripheral manifestation of spinal cord transection

Resumen

Nota bibliográfica

ASJC Scopus Subject Areas

PubMed: MeSH publication types

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