Regional differences in connexin32 and connexin43 messenger RNAs in rat brain

Christian C.G. Naus, Daniel J. Belliveau, John F. Bechberger

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

43 Citas (Scopus)

Resumen

The regional distribution of gap junction mRNAs was examined in the adult rat brain. The level of connexin43 mRNA is more abundant than connexin32, being homogeneously distributed throughout different regions of brain. In contrast, there is dramatic heterogeneity in the level of connexin32 mRNA, with the highest level in the hindbrain. These results suggest that the gap junction genes are differentially expressed in regions of the adult rat brain.

Idioma originalEnglish
Páginas (desde-hasta)297-302
Número de páginas6
PublicaciónNeuroscience Letters
Volumen111
N.º3
DOI
EstadoPublished - abr. 6 1990
Publicado de forma externa

Nota bibliográfica

Funding Information:
The authors are grateful to Dr. David Paul for his generous provision of the connexin cDNAs, and to Dr. D. Denhardt for the 18S cDNA used in this study. This research was supported by grants from the Hospital for Sick Children Foundation (Grant 88-05) and the Ministry of Community and Social Services, Ontario, Canada, administered by the Research and Program Evaluation Unit, in co-operation with the Ontario Mental Health Foundation, funded from the 'Interprovincial' Lottery Research Program. C.C.G.N. is a Scholar of the Medical Research Council of Canada, and D.J.B. is a holder of an NSERC Postgraduate Scholarship.

ASJC Scopus Subject Areas

  • General Neuroscience

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