Resumen
The regional distribution of gap junction mRNAs was examined in the adult rat brain. The level of connexin43 mRNA is more abundant than connexin32, being homogeneously distributed throughout different regions of brain. In contrast, there is dramatic heterogeneity in the level of connexin32 mRNA, with the highest level in the hindbrain. These results suggest that the gap junction genes are differentially expressed in regions of the adult rat brain.
Idioma original | English |
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Páginas (desde-hasta) | 297-302 |
Número de páginas | 6 |
Publicación | Neuroscience Letters |
Volumen | 111 |
N.º | 3 |
DOI | |
Estado | Published - abr. 6 1990 |
Publicado de forma externa | Sí |
Nota bibliográfica
Funding Information:The authors are grateful to Dr. David Paul for his generous provision of the connexin cDNAs, and to Dr. D. Denhardt for the 18S cDNA used in this study. This research was supported by grants from the Hospital for Sick Children Foundation (Grant 88-05) and the Ministry of Community and Social Services, Ontario, Canada, administered by the Research and Program Evaluation Unit, in co-operation with the Ontario Mental Health Foundation, funded from the 'Interprovincial' Lottery Research Program. C.C.G.N. is a Scholar of the Medical Research Council of Canada, and D.J.B. is a holder of an NSERC Postgraduate Scholarship.
ASJC Scopus Subject Areas
- General Neuroscience