The effect of myocardial force on coronary transmural flow distribution

Gerald A. Klassen; Danuta T. Zborowska-Sluis

doi:10.1093/cvr/13.7.365

The effect of myocardial force on coronary transmural flow distribution

Gerald A. Klassen, Danuta T. Zborowska-Sluis

Producción científica: Contribución a una revista › Artículo de revisión › revisión exhaustiva

5 Citas (Scopus)

Resumen

Summary: The role of myocardial force as a determinant of transmural coronary flow distribution was examined in the presence and absence of autoregulation by infusing calcium chloride into a segment of the left coronary system. The concentration of calcium used was adequate to increase force but did not alter coronary pressure or endoventricular pressure. No alterations in transmural gradients of flow were observed following increased regional force. These results suggest that increases in regional force are not of importance as a determinant of transmural blood flow.

Idioma original	English
Páginas (desde-hasta)	365-369
Número de páginas	5
Publicación	Cardiovascular Research
Volumen	13
N.º	7
DOI	https://doi.org/10.1093/cvr/13.7.365
Estado	Published - jul. 1979
Publicado de forma externa	Sí

Nota bibliográfica

Funding Information:
Supported by grants from the Medical Research Council of Canada, MT 3238 and the Quebec Heart Foundation.

ASJC Scopus Subject Areas

Physiology
Cardiology and Cardiovascular Medicine
Physiology (medical)

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title = "The effect of myocardial force on coronary transmural flow distribution",

abstract = "Summary: The role of myocardial force as a determinant of transmural coronary flow distribution was examined in the presence and absence of autoregulation by infusing calcium chloride into a segment of the left coronary system. The concentration of calcium used was adequate to increase force but did not alter coronary pressure or endoventricular pressure. No alterations in transmural gradients of flow were observed following increased regional force. These results suggest that increases in regional force are not of importance as a determinant of transmural blood flow.",

author = "Klassen, {Gerald A.} and Zborowska-Sluis, {Danuta T.}",

note = "Funding Information: Supported by grants from the Medical Research Council of Canada, MT 3238 and the Quebec Heart Foundation.",

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T1 - The effect of myocardial force on coronary transmural flow distribution

AU - Klassen, Gerald A.

AU - Zborowska-Sluis, Danuta T.

N1 - Funding Information: Supported by grants from the Medical Research Council of Canada, MT 3238 and the Quebec Heart Foundation.

PY - 1979/7

Y1 - 1979/7

N2 - Summary: The role of myocardial force as a determinant of transmural coronary flow distribution was examined in the presence and absence of autoregulation by infusing calcium chloride into a segment of the left coronary system. The concentration of calcium used was adequate to increase force but did not alter coronary pressure or endoventricular pressure. No alterations in transmural gradients of flow were observed following increased regional force. These results suggest that increases in regional force are not of importance as a determinant of transmural blood flow.

AB - Summary: The role of myocardial force as a determinant of transmural coronary flow distribution was examined in the presence and absence of autoregulation by infusing calcium chloride into a segment of the left coronary system. The concentration of calcium used was adequate to increase force but did not alter coronary pressure or endoventricular pressure. No alterations in transmural gradients of flow were observed following increased regional force. These results suggest that increases in regional force are not of importance as a determinant of transmural blood flow.

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M3 - Review article

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VL - 13

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EP - 369

JO - Cardiovascular Research

JF - Cardiovascular Research

IS - 7

ER -

The effect of myocardial force on coronary transmural flow distribution

Resumen

Nota bibliográfica

ASJC Scopus Subject Areas

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