The Prevention and Management of Infections in Children with Asplenia or Hyposplenia

Victoria E. Price; Victor S. Blanchette; E. Lee Ford-Jones

doi:10.1016/j.idc.2007.07.002

The Prevention and Management of Infections in Children with Asplenia or Hyposplenia

Victoria E. Price, Victor S. Blanchette, E. Lee Ford-Jones

Medicine

Producción científica: Contribución a una revista › Artículo de revisión › revisión exhaustiva

65 Citas (Scopus)

Resumen

Overwhelming sepsis remains a significant complication of asplenia and hyposplenia. The mainstays of prevention are education, immunization, and prophylactic antibiotics. Evidence to base recommendation and guidelines is lacking. Such decisions as the specific immunizations required, the timing of immunizations, the duration of antibiotic prophylaxis, and the prevention of overwhelming postsplenectomy sepsis in children undergoing splenectomy are often empiric. This article reviews the current literature on the prevention and management of severe infections in children with underlying asplenia or hyposplenia.

Idioma original	English
Páginas (desde-hasta)	697-710
Número de páginas	14
Publicación	Infectious Disease Clinics of North America
Volumen	21
N.º	3
DOI	https://doi.org/10.1016/j.idc.2007.07.002
Estado	Published - sep. 2007

ASJC Scopus Subject Areas

Microbiology (medical)
Infectious Diseases

ODS de las Naciones Unidas

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abstract = "Overwhelming sepsis remains a significant complication of asplenia and hyposplenia. The mainstays of prevention are education, immunization, and prophylactic antibiotics. Evidence to base recommendation and guidelines is lacking. Such decisions as the specific immunizations required, the timing of immunizations, the duration of antibiotic prophylaxis, and the prevention of overwhelming postsplenectomy sepsis in children undergoing splenectomy are often empiric. This article reviews the current literature on the prevention and management of severe infections in children with underlying asplenia or hyposplenia.",

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N2 - Overwhelming sepsis remains a significant complication of asplenia and hyposplenia. The mainstays of prevention are education, immunization, and prophylactic antibiotics. Evidence to base recommendation and guidelines is lacking. Such decisions as the specific immunizations required, the timing of immunizations, the duration of antibiotic prophylaxis, and the prevention of overwhelming postsplenectomy sepsis in children undergoing splenectomy are often empiric. This article reviews the current literature on the prevention and management of severe infections in children with underlying asplenia or hyposplenia.

AB - Overwhelming sepsis remains a significant complication of asplenia and hyposplenia. The mainstays of prevention are education, immunization, and prophylactic antibiotics. Evidence to base recommendation and guidelines is lacking. Such decisions as the specific immunizations required, the timing of immunizations, the duration of antibiotic prophylaxis, and the prevention of overwhelming postsplenectomy sepsis in children undergoing splenectomy are often empiric. This article reviews the current literature on the prevention and management of severe infections in children with underlying asplenia or hyposplenia.

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The Prevention and Management of Infections in Children with Asplenia or Hyposplenia

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