Paola Marcato

2023

The Expanding Role of Cancer Stem Cell Marker ALDH1A3 in Cancer and Beyond

McLean, M. E., MacLean, M. R., Cahill, H. F., Arun, R. P., Walker, O. L., Wasson, M. C. D., Fernando, W., Venkatesh, J. & Marcato, P., janv. 2023, Dans: Cancers. 15, 2, 492.

Résultat de recherche: Review article › examen par les pairs

Accès libre

23 Citations (Scopus)

2022

Breast Cancer Subtype-Specific miRNAs: Networks, Impacts, and the Potential for Intervention

Arun, R. P., Cahill, H. F. & Marcato, P., mars 2022, Dans: Biomedicines. 10, 3, 651.

Résultat de recherche: Review article › examen par les pairs

Accès libre

22 Citations (Scopus)

Breast Cancer Xenograft Murine Models

Fernando, W., Coyle, K. M. & Marcato, P., 2022, Dans: Methods in Molecular Biology. 2508, p. 31-44 14 p.

Medicine

Résultat de recherche: Article › examen par les pairs

Comparative pan-cancer transcriptomics reveals that aberrant expression of long non-coding RNAs define cancers, tumor progression and immune cell exclusion

Wasson, M. C., Brown, J., Venkatesh, J. & Marcato, P., oct. 2022, Dans: European Journal of Cancer. 174, p. S97

Medicine

Résultat de recherche: Article › examen par les pairs

Isolation of cancer stem cells from cultured breast cancer cells and xenografted breast tumors based on aldehyde dehydrogenase activity

Fernando, W., Rowter, D., Arun, R. P., Venkatesh, J. & Marcato, P., 2022, (Accepted/In press) Methods in Cell Biology. Academic Press Inc., (Methods in Cell Biology).

Medicine

Résultat de recherche: Chapter

Metabolite profiling reveals a connection between aldehyde dehydrogenase 1A3 and GABA metabolism in breast cancer metastasis

Dahn, M. L., Walsh, H. R., Dean, C. A., Giacomantonio, M. A., Fernando, W., Murphy, J. P., Walker, O. L., Wasson, M. C. D., Gujar, S., Pinto, D. M. & Marcato, P., janv. 2022, Dans: Metabolomics. 18, 1, 9.

Résultat de recherche: Article › examen par les pairs

Accès libre

17 Citations (Scopus)

The Prostaglandin E2 Pathway and Breast Cancer Stem Cells: Evidence of Increased Signaling and Potential Targeting

Walker, O. L., Dahn, M. L., Power Coombs, M. R. & Marcato, P., janv. 19 2022, Dans: Frontiers in Oncology. 11, 791696.

Résultat de recherche: Review article › examen par les pairs

Accès libre

25 Citations (Scopus)

2021

An in vivo genome-wide shRNA screen identifies BCL6 as a targetable biomarker of paclitaxel resistance in breast cancer

Sultan, M., Nearing, J. T., Brown, J. M., Huynh, T. T., Cruickshank, B. M., Lamoureaux, E., Vidovic, D., Dahn, M. L., Fernando, W., Coyle, K. M., Giacomantonio, C. A., Langille, M. G. I. & Marcato, P., août 2021, Dans: Molecular Oncology. 15, 8, p. 2046-2064 19 p.

Résultat de recherche: Article › examen par les pairs

Accès libre

8 Citations (Scopus)

Datasets exploring putative lncRNA-miRNA-mRNA axes in breast cancer cell lines

Wasson, M. C. D., Brown, J. M., Venkatesh, J., Fernando, W. & Marcato, P., août 2021, Dans: Data in Brief. 37, 107241.

Résultat de recherche: Article › examen par les pairs

Accès libre

7 Citations (Scopus)

Human-specific GAPDH qRT-PCR is an accurate and sensitive method of xenograft metastasis quantification

Dahn, M. L., Dean, C. A., Jo, D. B., Coyle, K. M. & Marcato, P., mars 12 2021, Dans: Molecular Therapy - Methods and Clinical Development. 20, p. 398-408 11 p.

Résultat de recherche: Article › examen par les pairs

Accès libre

19 Citations (Scopus)

In Vivo Genome-Wide Pooled RNAi Screens in Cancer Cells to Identify Determinants of Chemotherapy/Drug Response

Dahn, M. L. & Marcato, P., 2021, Methods in Molecular Biology. Humana Press Inc., p. 189-200 12 p. (Methods in Molecular Biology; vol. 2381).

Résultat de recherche: Chapter

1 Citation (Scopus)

LncRNA-miRNA axes in breast cancer: Novel points of interaction for strategic attack

Venkatesh, J., Wasson, M. C. D., Brown, J. M., Fernando, W. & Marcato, P., juill. 1 2021, Dans: Cancer Letters. 509, p. 81-88 8 p.

Résultat de recherche: Short survey › examen par les pairs

Accès libre

129 Citations (Scopus)

Lncrna part1 promotes proliferation and migration, is associated with cancer stem cells, and alters the mirna landscape in triple‐negative breast cancer

Cruickshank, B. M., Wasson, M. C. D., Brown, J. M., Fernando, W., Venkatesh, J., Walker, O. L., Morales‐quintanilla, F., Dahn, M. L., Dean, C. A., Vidovic, D., Vaniderstine, C., Dellaire, G. & Marcato, P., juin 1 2021, Dans: Cancers. 13, 11, 2644.

Résultat de recherche: Article › examen par les pairs

Accès libre

18 Citations (Scopus)

Profiling non-small cell lung cancer reveals that PD-L1 is associated with wild type EGFR and vascular invasion, and immunohistochemistry quantification of PDL1 correlates weakly with RT-qPCR

Alwithenani, A., Bethune, D., Castonguay, M., Drucker, A., Flowerdew, G., Forsythe, M., French, D., Fris, J., Greer, W., Henteleff, H., MacNeil, M., Marignani, P., Morzycki, W., Plourde, M., Snow, S., Marcato, P. & Xu, Z., mai 2021, Dans: PLoS One. 16, 5 May, e0251080.

Résultat de recherche: Article › examen par les pairs

Accès libre

11 Citations (Scopus)

Targeting the roots of recurrence: new strategies for eliminating therapy-resistant breast cancer stem cells

Dahn, M. L. & Marcato, P., janv. 2021, Dans: Cancers. 13, 1, p. 1-5 5 p., 54.

Résultat de recherche: Editorial › examen par les pairs

Accès libre

5 Citations (Scopus)

Triple-negative breast cancer and the COVID-19 pandemic: Clinical management perspectives and potential consequences of infection

Brown, J. M., Wasson, M. C. D. & Marcato, P., janv. 2 2021, Dans: Cancers. 13, 2, p. 1-13 13 p., 296.

Résultat de recherche: Article › examen par les pairs

Accès libre

6 Citations (Scopus)

2020

ALDH1A3-regulated long non-coding RNA NRAD1 is a potential novel target for triple-negative breast tumors and cancer stem cells

Vidovic, D., Huynh, T. T., Konda, P., Dean, C., Cruickshank, B. M., Sultan, M., Coyle, K. M., Gujar, S. & Marcato, P., janv. 1 2020, Dans: Cell Death and Differentiation. 27, 1, p. 363-378 16 p.

Résultat de recherche: Article › examen par les pairs

Accès libre

93 Citations (Scopus)

Decitabine response in breast cancer requires efficient drug processing and is not limited by multidrug resistance

Dahn, M. L., Cruickshank, B. M., Jackson, A. J., Dean, C., Holloway, R. W., Hall, S. R., Coyle, K. M., Maillet, H., Waisman, D. M., Goralski, K. B., Giacomantonio, C. A., Weaver, I. C. G. & Marcato, P., mai 1 2020, Dans: Molecular Cancer Therapeutics. 19, 5, p. 1110-1122 13 p.

Résultat de recherche: Article › examen par les pairs

24 Citations (Scopus)

S100A10 has a critical regulatory function in mammary tumor growth and metastasis: Insights using MMTV-PyMT oncomice and clinical patient sample analysis

Bharadwaj, A. G., Dahn, M. L., Liu, R. Z., Colp, P., Thomas, L. N., Holloway, R. W., Marignani, P. A., Too, C. K. L., Barnes, P. J., Godbout, R., Marcato, P. & Waisman, D. M., déc. 2020, Dans: Cancers. 12, 12, p. 1-22 22 p., 3673.

Résultat de recherche: Article › examen par les pairs

Accès libre

10 Citations (Scopus)

The Missing Lnc: The Potential of Targeting Triple-Negative Breast Cancer and Cancer Stem Cells by Inhibiting Long Non-Coding RNAs

Brown, J. M., Wasson, M. C. D. & Marcato, P., mars 20 2020, Dans: Cells. 9, 3

Résultat de recherche: Review article › examen par les pairs

Accès libre

31 Citations (Scopus)

2019

Phloridzin docosahexaenoate, a novel fatty acid ester of a plant polyphenol, inhibits mammary carcinoma cell metastasis

Fernando, W., Coyle, K., Marcato, P., Vasantha Rupasinghe, H. P. & Hoskin, D. W., nov. 28 2019, Dans: Cancer Letters. 465, p. 68-81 14 p.

Medicine

Résultat de recherche: Article › examen par les pairs

22 Citations (Scopus)

Retinoic acid and arsenic trioxide induce lasting differentiation and demethylation of target genes in APL cells

Huynh, T. T., Sultan, M., Vidovic, D., Dean, C. A., Cruickshank, B. M., Lee, K., Loung, C. Y., Holloway, R. W., Hoskin, D. W., Waisman, D. M., Weaver, I. C. G. & Marcato, P., déc. 1 2019, Dans: Scientific Reports. 9, 1, 9414.

Résultat de recherche: Article › examen par les pairs

Accès libre

32 Citations (Scopus)

TAP73 modifies metabolism and positively regulates growth of cancer stem–like cells in a redox-sensitive manner

Sharif, T., Dai, C., Martell, E., Ghassemi-Rad, M. S., Hanes, M. R., Murphy, P. J., Kennedy, B. E., Venugopal, C., Subapanditha, M., Giacomantonio, C. A., Marcato, P., Singh, S. K. & Gujar, S., 2019, Dans: Clinical Cancer Research. 25, 6, p. 2001-2017 17 p.

Résultat de recherche: Article › examen par les pairs

24 Citations (Scopus)

The flick of a switch: Conferring survival advantage to breast cancer stem cells through metabolic plasticity

Walsh, H. R., Cruickshank, B. M., Brown, J. M. & Marcato, P., 2019, Dans: Frontiers in Oncology. 9, AUG, 753.

Medicine

Résultat de recherche: Short survey › examen par les pairs

Accès libre

23 Citations (Scopus)

TRPM2 ion channel promotes gastric cancer migration, invasion and tumor growth through the AKT signaling pathway

Almasi, S., Sterea, A. M., Fernando, W., Clements, D. R., Marcato, P., Hoskin, D. W., Gujar, S. & El Hiani, Y., déc. 1 2019, Dans: Scientific Reports. 9, 1, 4182.

Résultat de recherche: Article › examen par les pairs

Accès libre

55 Citations (Scopus)

2018

ALDH1A3 Is the Key Isoform That Contributes to Aldehyde Dehydrogenase Activity and Affects in Vitro Proliferation in Cardiac Atrial Appendage Progenitor Cells

Puttini, S., Plaisance, I., Barile, L., Cervio, E., Milano, G., Marcato, P., Pedrazzini, T. & Vassalli, G., juill. 24 2018, Dans: Frontiers in Cardiovascular Medicine. 5, 90.

Medicine

Résultat de recherche: Article › examen par les pairs

Accès libre

20 Citations (Scopus)

Dna methylation predicts the response of triple-negative breast cancers to all-trans retinoic acid

Coyle, K. M., Dean, C. A., Thomas, M. L., Vidovic, D., Giacomantonio, C. A., Helyer, L. & Marcato, P., nov. 2018, Dans: Cancers. 10, 11, 397.

Medicine

Résultat de recherche: Article › examen par les pairs

Accès libre

22 Citations (Scopus)

Dying to be noticed: Epigenetic regulation of immunogenic cell death for cancer immunotherapy

Cruickshank, B., Giacomantonio, M., Marcato, P., McFarland, S., Pol, J. & Gujar, S., avr. 3 2018, Dans: Frontiers in Immunology. 9, APR, 654.

Résultat de recherche: Short survey › examen par les pairs

Accès libre

49 Citations (Scopus)

Epigenetic modifications as biomarkers of tumor development, therapy response, and recurrence across the cancer care continuum

Thomas, M. L. & Marcato, P., avr. 2018, Dans: Cancers. 10, 4, 101.

Résultat de recherche: Review article › examen par les pairs

Accès libre

59 Citations (Scopus)

Epigenetic Silencing of TAP1 in Aldefluor ⁺ Breast Cancer Stem Cells Contributes to Their Enhanced Immune Evasion

Sultan, M., Vidovic, D., Paine, A. S., Huynh, T. T., Coyle, K. M., Thomas, M. L., Cruickshank, B. M., Dean, C. A., Clements, D. R., Kim, Y., Lee, K., Gujar, S. A., Weaver, I. C. G. & Marcato, P., mai 2018, Dans: Stem Cells. 36, 5, p. 641-654 14 p.

Résultat de recherche: Article › examen par les pairs

Accès libre

49 Citations (Scopus)

Regulation of cell surface protease receptor S100A10 by retinoic acid therapy in acute promyelocytic leukemia (APL)^☆

Holloway, R. W., Thomas, M. L., Cohen, A. M., Bharadwaj, A. G., Rahman, M., Marcato, P., Marignani, P. A. & Waisman, D. M., sept. 1 2018, Dans: Cell Death and Disease. 9, 9, 920.

Résultat de recherche: Article › examen par les pairs

Accès libre

13 Citations (Scopus)

2017

Genetic mutations and epigenetic modifications: Driving cancer and informing precision medicine

Coyle, K. M., Boudreau, J. E. & Marcato, P., 2017, Dans: BioMed Research International. 2017, 9620870.

Résultat de recherche: Review article › examen par les pairs

Accès libre

54 Citations (Scopus)

Hide-and-seek: The interplay between cancer stem cells and the immune system

Sultan, M., Coyle, K. M., Vidovic, D., Thomas, M. L., Gujar, S. & Marcato, P., févr. 1 2017, Dans: Carcinogenesis. 38, 2, p. 107-118 12 p., bgw115.

Medicine

Résultat de recherche: Review article › examen par les pairs

Accès libre

80 Citations (Scopus)

Profiling of the transcriptional response to all-Trans retinoic acid in breast cancer cells reveals RARE-independent mechanisms of gene expression

Coyle, K. M., Maxwell, S., Thomas, M. L. & Marcato, P., déc. 1 2017, Dans: Scientific Reports. 7, 1, 16684.

Medicine

Résultat de recherche: Article › examen par les pairs

Accès libre

23 Citations (Scopus)

2016

Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1

Coyle, K. M., Murphy, J. P., Vidovic, D., Vaghar-Kashani, A., Dean, C. A., Sultan, M., Clements, D., Wallace, M., Thomas, M. L., Hundert, A., Giacomantonio, C. A., Helyer, L., Gujar, S. A., Lee, P. W. K., Weaver, I. C. G. & Marcato, P., 2016, Dans: Oncotarget. 7, 28, p. 44096-44112 17 p.

Medicine

Résultat de recherche: Article › examen par les pairs

Accès libre

26 Citations (Scopus)

Citral reduces breast tumor growth by inhibiting the cancer stem cell marker ALDH1A3

Thomas, M. L., de Antueno, R., Coyle, K. M., Sultan, M., Cruickshank, B. M., Giacomantonio, M. A., Giacomantonio, C. A., Duncan, R. & Marcato, P., nov. 1 2016, Dans: Molecular Oncology. 10, 9, p. 1485-1496 12 p.

Résultat de recherche: Article › examen par les pairs

Accès libre

76 Citations (Scopus)

The NAD⁺ salvage pathway modulates cancer cell viability via p73

Sharif, T., Ahn, D. G., Liu, R. Z., Pringle, E., Martell, E., Dai, C., Nunokawa, A., Kwak, M., Clements, D., Murphy, J. P., Dean, C., Marcato, P., McCormick, C., Godbout, R., Gujar, S. A. & Lee, P. W. K., avr. 1 2016, Dans: Cell Death and Differentiation. 23, 4, p. 669-680 12 p.

Résultat de recherche: Article › examen par les pairs

Accès libre

55 Citations (Scopus)

2015

Aldehyde dehydrogenase 1A3 influences breast cancer progression via differential retinoic acid signaling

Marcato, P., Dean, C. A., Liu, R. Z., Coyle, K. M., Bydoun, M., Wallace, M., Clements, D., Turner, C., Mathenge, E. G., Gujar, S. A., Giacomantonio, C. A., Mackey, J. R., Godbout, R. & Lee, P. W. K., janv. 1 2015, Dans: Molecular Oncology. 9, 1, p. 17-31 15 p.

Medicine

Résultat de recherche: Article › examen par les pairs

Accès libre

98 Citations (Scopus)

A STAT3-NFkB/DDIT3/CEBPβ axis modulates ALDH1A3 expression in chemoresistant cell subpopulations

Canino, C., Luo, Y. Y., Marcato, P., Blandino, G., Pass, H. I. & Cioce, M., 2015, Dans: Oncotarget. 6, 14, p. 12637-12653 17 p.

Résultat de recherche: Article › examen par les pairs

Accès libre

72 Citations (Scopus)

Cancer stem cells and chemoresistance: Strategies to overcome therapeutic resistance

Thomas, M. L., Coyle, K. M., Sultan, M. & Marcato, P., janv. 1 2015, Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology. Springer International Publishing, p. 477-518 42 p.

Résultat de recherche: Chapter

2 Citations (Scopus)

Newly recruited CD11b⁺, GR-1⁺, Ly6C^high myeloid cells augment tumor-associated immunosuppression immediately following the therapeutic administration of oncolytic reovirus

Clements, D. R., Sterea, A. M., Kim, Y., Helson, E., Dean, C. A., Nunokawa, A., Coyle, K. M., Sharif, T., Marcato, P., Gujar, S. A. & Lee, P. W. K., mai 1 2015, Dans: Journal of Immunology. 194, 9, p. 4397-4412 16 p.

Medicine

Résultat de recherche: Article › examen par les pairs

Accès libre

30 Citations (Scopus)

Targeting key stemness-related pathways in human cancers

Coyle, K. M., Thomas, M. L., Sultan, M. & Marcato, P., janv. 1 2015, Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology. Springer International Publishing, p. 393-443 51 p.

Résultat de recherche: Chapter

1 Citation (Scopus)

2014

Core Needle Biopsy of Breast Cancer Tumors Increases Distant Metastases in a Mouse Model

Mathenge, E. G., Dean, C. A., Clements, D., Vaghar-Kashani, A., Photopoulos, S., Coyle, K. M., Giacomantonio, M., Malueth, B., Nunokawa, A., Jordan, J., Lewis, J. D., Gujar, S. A., Marcato, P., Lee, P. W. K. & Giacomantonio, C. A., 2014, Dans: Neoplasia. 16, 11, p. 950-960 11 p.

Medicine

Résultat de recherche: Article › examen par les pairs

Accès libre

76 Citations (Scopus)

Gemcitabine enhances the efficacy of reovirus-based oncotherapy through anti-tumour immunological mechanisms

Gujar, S. A., Clements, D., Dielschneider, R., Helson, E., Marcato, P. & Lee, P. W. K., 2014, Dans: British Journal of Cancer. 110, 1, p. 83-93 11 p.

Medicine

Résultat de recherche: Article › examen par les pairs

Accès libre

52 Citations (Scopus)

2013

Activation of p53 by Chemotherapeutic Agents Enhances Reovirus Oncolysis

Pan, D., Marcato, P., Ahn, D. G., Gujar, S., Pan, L. Z., Shmulevitz, M. & Lee, P. W. K., janv. 16 2013, Dans: PLoS One. 8, 1, e54006.

Medicine

Résultat de recherche: Article › examen par les pairs

Accès libre

19 Citations (Scopus)

Breast Cancer Genomics

Bydoun, M., Marcato, P. & Dellaire, G., déc. 2013, Cancer Genomics: From Bench to Personalized Medicine. Elsevier Inc., p. 213-232 20 p.

Résultat de recherche: Chapter

7 Citations (Scopus)

Multifaceted therapeutic targeting of ovarian peritoneal carcinomatosis through virus-induced immunomodulation

Gujar, S., Dielschneider, R., Clements, D., Helson, E., Shmulevitz, M., Marcato, P., Pan, D., Pan, L. Z., Ahn, D. G., Alawadhi, A. & Lee, P. W. K., févr. 2013, Dans: Molecular Therapy. 21, 2, p. 338-347 10 p.

Résultat de recherche: Article › examen par les pairs

Accès libre