Résumé
Systemic administration of 4-aminopyridine (4-AP) increased the size of the cutaneous receptive fields of 9 of the 15 dorsal horn cells tested. These receptive fields were on the feet and toes of the hind limbs of cats. Receptive field sizes increased with increasing doses of 4-AP. However, 4-AP administration did not change the responses of dorsal horn cells to graded mechanical stimuli administered near the centers of their receptive fields.
| Langue d'origine | English |
|---|---|
| Pages (de-à) | 398-402 |
| Nombre de pages | 5 |
| Journal | Brain Research |
| Volume | 343 |
| Numéro de publication | 2 |
| DOI | |
| Statut de publication | Published - sept. 23 1985 |
| Publié à l'externe | Oui |
Note bibliographique
Funding Information:This work was supported by grants from the UMDNJ Foundation (44-84), NIH (NS-19187 to H. M. G.) and NSF (BNS-8205598 to M. D. E.). We thank Suzan Harris and Pat Masarachia for technical assistance. Professor P. D. Wall suggested to us the use of 4-AP, and kindly shared preliminary results from similar work performed by himself and his colleagues, Drs. N. E. Saad6 and S. J. Jabbur.
ASJC Scopus Subject Areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology