Breach delivery: Increased solute uptake points to a defective skin barrier in atopic dermatitis

W. H. Irwin McLean; Peter R. Hull

doi:10.1038/sj.jid.5700609

Breach delivery: Increased solute uptake points to a defective skin barrier in atopic dermatitis

W. H. Irwin McLean, Peter R. Hull

Résultat de recherche: Comment/debate › examen par les pairs

28 Citations (Scopus)

Résumé

Evidence is now emerging for enhanced penetration of chemical solutes into uninvolved skin of atopic dermatitis patients. Along with the recent discovery of prevalent null mutations in the gene encoding filaggrin, a protein essential for stratum corneum formation, these data point to an innate epidermal-barrier defect in atopy.

Langue d'origine	English
Pages (de-à)	8-10
Nombre de pages	3
Journal	Journal of Investigative Dermatology
Volume	127
Numéro de publication	1
DOI	https://doi.org/10.1038/sj.jid.5700609
Statut de publication	Published - janv. 27 2007
Publié à l'externe	Oui

ASJC Scopus Subject Areas

Biochemistry
Molecular Biology
Dermatology
Cell Biology

PubMed: MeSH publication types

Journal Article
Comment

Accès au document

10.1038/sj.jid.5700609

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Breach delivery: Increased solute uptake points to a defective skin barrier in atopic dermatitis

Résumé

ASJC Scopus Subject Areas

PubMed: MeSH publication types

Accès au document

Autres fichiers et liens

Empreinte numérique

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