Non-random occurrence of 7-14 translocations in human lymphocyte cultures

J. P. Welch; C. L.Y. Lee

doi:10.1038/255241a0

Non-random occurrence of 7-14 translocations in human lymphocyte cultures

J. P. Welch, C. L.Y. Lee

Medicine

Medicine

Résultat de recherche: Article › examen par les pairs

71 Citations (Scopus)

Résumé

SOMATIC cells dividing in vitro occasionally show chromosome recombination between non-homologues most often in situations associated with an increased frequency of chromosome breakage and reunion^1,2 their occurrence being recognised by the observation of exchange figures. With the advent of new techniques for chromosome identification³ it is now possible to identify the chromosomes involved in these rearrangements and to recognise some translocations which might otherwise be missed.

Langue d'origine	English
Pages (de-à)	241-242
Nombre de pages	2
Journal	Nature
Volume	255
Numéro de publication	5505
DOI	https://doi.org/10.1038/255241a0
Statut de publication	Published - 1975

ASJC Scopus Subject Areas

General

PubMed: MeSH publication types

Journal Article
Research Support, U.S. Gov't, P.H.S.

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10.1038/255241a0

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abstract = "SOMATIC cells dividing in vitro occasionally show chromosome recombination between non-homologues most often in situations associated with an increased frequency of chromosome breakage and reunion1,2 their occurrence being recognised by the observation of exchange figures. With the advent of new techniques for chromosome identification3 it is now possible to identify the chromosomes involved in these rearrangements and to recognise some translocations which might otherwise be missed.",

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AB - SOMATIC cells dividing in vitro occasionally show chromosome recombination between non-homologues most often in situations associated with an increased frequency of chromosome breakage and reunion1,2 their occurrence being recognised by the observation of exchange figures. With the advent of new techniques for chromosome identification3 it is now possible to identify the chromosomes involved in these rearrangements and to recognise some translocations which might otherwise be missed.

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Non-random occurrence of 7-14 translocations in human lymphocyte cultures

Résumé

ASJC Scopus Subject Areas

PubMed: MeSH publication types

Accès au document

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