TY - JOUR
T1 - Primary intraocular lymphoma arising during methotrexate treatment of temporal arteritis
AU - Rizkalla, Kamilia
AU - Rodrigues, Sylvia
AU - Proulx, Alain
AU - Tingey, David P.
AU - Heathcote, J. Godfrey
PY - 2005/10
Y1 - 2005/10
N2 - Case report: Primary intraocular lymphoma arose over a period of 9 months in the left eye of an 81-year-old woman who was blind in both eyes from temporal arteritis. During this period, she was treated with prednisone and methotrexate. Following a sudden total hyphema, the eye was enucleated. Examination revealed that, in addition to iris neovascularisation and central retinal artery occlusion, the neurosensory retina was replaced by atypical lymphocytes. Comments: Histological and immunohistochemical studies confirmed the presence of a lymphoma with features indicative of an immunosuppression- related disorder. The relationship of the lymphoma to the vascular changes within the eye is discussed.
AB - Case report: Primary intraocular lymphoma arose over a period of 9 months in the left eye of an 81-year-old woman who was blind in both eyes from temporal arteritis. During this period, she was treated with prednisone and methotrexate. Following a sudden total hyphema, the eye was enucleated. Examination revealed that, in addition to iris neovascularisation and central retinal artery occlusion, the neurosensory retina was replaced by atypical lymphocytes. Comments: Histological and immunohistochemical studies confirmed the presence of a lymphoma with features indicative of an immunosuppression- related disorder. The relationship of the lymphoma to the vascular changes within the eye is discussed.
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U2 - 10.1016/S0008-4182(05)80050-X
DO - 10.1016/S0008-4182(05)80050-X
M3 - Article
AN - SCOPUS:27644560893
SN - 0008-4182
VL - 40
SP - 585
EP - 592
JO - Canadian Journal of Ophthalmology
JF - Canadian Journal of Ophthalmology
IS - 5
ER -