Résumé
A new model system for inducing reaginic antibody formation in mice is presented, namely a single injection of rabbit anti mouse thymocyte serum (RAMTS). Using this model it is shown that X irradiation (450 rad) administered to CBA mice 24 hr after a single injection of RAMTS or IgG (RAMTS) results in a sustained moderately high level of reagins against rabbit serum proteins with a concomitant barely detectable level (titer 1:5) of γ1 antibodies. Splenectomy and thymectomy had no demonstrable effect on reaginic antibody synthesis.
| Langue d'origine | English |
|---|---|
| Pages (de-à) | 780-788 |
| Nombre de pages | 9 |
| Journal | International Archives of Allergy and Applied Immunology |
| Volume | 45 |
| Numéro de publication | 5 |
| DOI | |
| Statut de publication | Published - 1973 |
ASJC Scopus Subject Areas
- Immunology and Allergy