Suprachiasmatic stimulation phase shifts rodent circadian rhythms

Benjamin Rusak; Gerard Groos

doi:10.1126/science.7063851

Suprachiasmatic stimulation phase shifts rodent circadian rhythms

Benjamin Rusak, Gerard Groos

Medicine

Medicine

Résultat de recherche: Article › examen par les pairs

104 Citations (Scopus)

Résumé

The integrity of the suprachiasmatic nuclei (SCN) of the hypothalamus is essential to the expression of normal circadian rhythms in rodents. Electrical stimulation of the SCN caused phase shifts and period changes in the freerunning feeding rhythms of rats and activity rhythms of hamsters. The phase response curve for SCN stimulation appears to parallel that for light pulses. These findings strengthen the hypothesis derived from lesion studies that the SCN are the dominant light-entrained oscillators in the rodent circadian system.

Langue d'origine	English
Pages (de-à)	1407-1409
Nombre de pages	3
Journal	Science
Volume	215
Numéro de publication	4538
DOI	https://doi.org/10.1126/science.7063851
Statut de publication	Published - 1982

ASJC Scopus Subject Areas

General

PubMed: MeSH publication types

Journal Article
Research Support, Non-U.S. Gov't

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10.1126/science.7063851

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title = "Suprachiasmatic stimulation phase shifts rodent circadian rhythms",

abstract = "The integrity of the suprachiasmatic nuclei (SCN) of the hypothalamus is essential to the expression of normal circadian rhythms in rodents. Electrical stimulation of the SCN caused phase shifts and period changes in the freerunning feeding rhythms of rats and activity rhythms of hamsters. The phase response curve for SCN stimulation appears to parallel that for light pulses. These findings strengthen the hypothesis derived from lesion studies that the SCN are the dominant light-entrained oscillators in the rodent circadian system.",

author = "Benjamin Rusak and Gerard Groos",

year = "1982",

doi = "10.1126/science.7063851",

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T1 - Suprachiasmatic stimulation phase shifts rodent circadian rhythms

AU - Rusak, Benjamin

AU - Groos, Gerard

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N2 - The integrity of the suprachiasmatic nuclei (SCN) of the hypothalamus is essential to the expression of normal circadian rhythms in rodents. Electrical stimulation of the SCN caused phase shifts and period changes in the freerunning feeding rhythms of rats and activity rhythms of hamsters. The phase response curve for SCN stimulation appears to parallel that for light pulses. These findings strengthen the hypothesis derived from lesion studies that the SCN are the dominant light-entrained oscillators in the rodent circadian system.

AB - The integrity of the suprachiasmatic nuclei (SCN) of the hypothalamus is essential to the expression of normal circadian rhythms in rodents. Electrical stimulation of the SCN caused phase shifts and period changes in the freerunning feeding rhythms of rats and activity rhythms of hamsters. The phase response curve for SCN stimulation appears to parallel that for light pulses. These findings strengthen the hypothesis derived from lesion studies that the SCN are the dominant light-entrained oscillators in the rodent circadian system.

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SP - 1407

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JO - Science

JF - Science

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ER -

Suprachiasmatic stimulation phase shifts rodent circadian rhythms

Résumé

ASJC Scopus Subject Areas

PubMed: MeSH publication types

Accès au document

Autres fichiers et liens

Empreinte numérique

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